| Company Name: |
BOC Sciences
|
| Tel: |
|
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:RQ-00311651
CAS:1257116-00-9
Remarks:RQ-00311651 is a novel T-type Ca channel inhibitor' which plays a role in neuropathic and visceral pain. RQ-00311651 notably inhibited T currents when tested at holding potentials of -65 ～ -60 mV' but
|
|
| | RQ-00311651 Basic information |
| Product Name: | RQ-00311651 | | Synonyms: | RQ-00311651;RQ00311651,RQ 00311651;Cyclopropanecarboxamide, 2-(1H-benzimidazol-2-yl)-N-[(1R)-1-[5-(2,2,2-trifluoroethoxy)-2-pyrazinyl]ethyl]-, (1S,2S)- | | CAS: | 1257116-00-9 | | MF: | C19H18F3N5O2 | | MW: | 405.37 | | EINECS: | | | Product Categories: | | | Mol File: | 1257116-00-9.mol |  |
| | RQ-00311651 Chemical Properties |
| Boiling point | 655.8±55.0 °C(Predicted) | | density | 1.425±0.06 g/cm3(Predicted) | | pka | 11.95±0.10(Predicted) |
| | RQ-00311651 Usage And Synthesis |
| Description | RQ-00311651 is a novel T-type Ca2+ channel blocker, in distinct rodent models for neuropathic and visceral pain. RQ-00311651 strongly suppressed T currents when tested at holding potentials of -65 ～ -60 mV, but not -80 mV, in the Cav3.1- or Cav3.2-expressing cells. RQ-00311651 also inhibited high K-induced Ca signaling in those cells. |
| | RQ-00311651 Preparation Products And Raw materials |
|