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BOC Sciences
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Product Name:RQ-00311651 CAS:1257116-00-9 Remarks:RQ-00311651 is a novel T-type Ca channel inhibitor' which plays a role in neuropathic and visceral pain. RQ-00311651 notably inhibited T currents when tested at holding potentials of -65 ~ -60 mV' but
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| RQ-00311651 Basic information |
Product Name: | RQ-00311651 | Synonyms: | RQ-00311651;RQ00311651,RQ 00311651;Cyclopropanecarboxamide, 2-(1H-benzimidazol-2-yl)-N-[(1R)-1-[5-(2,2,2-trifluoroethoxy)-2-pyrazinyl]ethyl]-, (1S,2S)- | CAS: | 1257116-00-9 | MF: | C19H18F3N5O2 | MW: | 405.37 | EINECS: | | Product Categories: | | Mol File: | 1257116-00-9.mol | ![RQ-00311651 Structure](CAS/20210111/GIF/1257116-00-9.gif) |
| RQ-00311651 Chemical Properties |
Boiling point | 655.8±55.0 °C(Predicted) | density | 1.425±0.06 g/cm3(Predicted) | pka | 11.95±0.10(Predicted) |
| RQ-00311651 Usage And Synthesis |
Description | RQ-00311651 is a novel T-type Ca2+ channel blocker, in distinct rodent models for neuropathic and visceral pain. RQ-00311651 strongly suppressed T currents when tested at holding potentials of -65 ~ -60 mV, but not -80 mV, in the Cav3.1- or Cav3.2-expressing cells. RQ-00311651 also inhibited high K-induced Ca signaling in those cells. |
| RQ-00311651 Preparation Products And Raw materials |
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