2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid

2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid Suppliers list
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Products Intro: Product Name:Milnacipran Impurity 18
CAS:32675-71-1
Purity:95% HPLC Package:10mg;25mg;50mg;100mg
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Products Intro: Product Name:DNA Methyltransferase Inhibitor - CAS 32675-71-1 - Calbiochem
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Products Intro: CAS:32675-71-1
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Products Intro: Product Name:Milnacipran Impurity 18
CAS:32675-71-1
Purity:95% Package:10mg;25mg;50mg;100mg
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Products Intro: Product Name:2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid
CAS:32675-71-1
Purity:95%+ Package:50G;100G
2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid Basic information
Product Name:2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid
Synonyms:2-(1,3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl)propanoic acid;DNA Methyltransferase Inhibitor - CAS 32675-71-1 - Calbiochem;1H-Indole-3-propanoic acid, α-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-;(Rac)-RG108
CAS:32675-71-1
MF:C19H14N2O4
MW:334.33
EINECS:
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Mol File:32675-71-1.mol
2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid Structure
2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid Chemical Properties
Boiling point 606.0±50.0 °C(Predicted)
density 1.502±0.06 g/cm3(Predicted)
storage temp. +2C to +8C
form Yellow solid
pka3.62±0.10(Predicted)
Safety Information
MSDS Information
2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid Usage And Synthesis
General DescriptionA cell-permeable, specific DNA methyltransferases inhibitor (IC50 = 115 nM for CpG methylase M.SssI) that displays anti-proliferative, but not cytotoxic, properties. Unlike the commonly used inhibitor 5-azacytidine, RG108 directly interacts with DNA methyltransferase active site via its carboxy group.
Biochem/physiol ActionsCell permeable: yes
2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid Preparation Products And Raw materials
Tag:2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid(32675-71-1) Related Product Information