Company Name: |
ChemStrong Scientific Co.,Ltd
|
Tel: |
0755-0755-66853366 13670046396 |
Email: |
sales@chem-strong.com |
Products Intro: |
Product Name:Milnacipran Impurity 18 CAS:32675-71-1 Purity:95% HPLC Package:10mg;25mg;50mg;100mg
|
Company Name: |
Sigma-Aldrich
|
Tel: |
021-61415566 800-8193336 |
Email: |
orderCN@merckgroup.com |
Products Intro: |
Product Name:DNA Methyltransferase Inhibitor - CAS 32675-71-1 - Calbiochem
|
|
| 2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid Basic information |
| 2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid Chemical Properties |
Boiling point | 606.0±50.0 °C(Predicted) | density | 1.502±0.06 g/cm3(Predicted) | storage temp. | +2C to +8C | form | Yellow solid | pka | 3.62±0.10(Predicted) |
| 2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid Usage And Synthesis |
General Description | A cell-permeable, specific DNA methyltransferases inhibitor (IC50 = 115 nM for CpG methylase M.SssI) that displays anti-proliferative, but not cytotoxic, properties. Unlike the commonly used inhibitor 5-azacytidine, RG108 directly interacts with DNA methyltransferase active site via its carboxy group. | Biochem/physiol Actions | Cell permeable: yes |
| 2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid Preparation Products And Raw materials |
|