Caulophine

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CAS:1159989-19-1
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CAS:1159989-19-1
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Caulophine Basic information
Product Name:Caulophine
Synonyms:Caulophine;9H-Fluoren-9-one, 3-[2-(dimethylamino)ethyl]-4,5-dihydroxy-1,6-dimethoxy-
CAS:1159989-19-1
MF:C19H21NO5
MW:343.37
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Mol File:1159989-19-1.mol
Caulophine Structure
Caulophine Chemical Properties
Boiling point 576.1±50.0 °C(Predicted)
density 1.306±0.06 g/cm3(Predicted)
pka7.45±0.20(Predicted)
Safety Information
MSDS Information
Caulophine Usage And Synthesis
UsesCaulophine is a fluoroketone alkaloid isolated from Caulophyllum robustum MAXIM. Caulophine has antioxidant activity and the ability to protect cardiomyocytes from oxidative and ischemic damage, providing potential value for coronary heart disease research[1].
DefinitionChEBI: Caulophine is a member of the class of fluoren-9-ones that is 9H-fluoren-9-one substituted by 2-(dimethylamino)ethyl group at position 3, hydroxy groups at positions 4 and 5 and two methoxy groups at positions 1 and 6 respectively. It is isolated from the radix of Caulophyllum robustum and exhibits anti-myocardial ischemia activity. It has a role as a metabolite and a cardiovascular drug. It is a member of fluoren-9-ones, a tertiary amino compound, a polyphenol, an aromatic ether and an alkaloid.
References[1] Kaiwei Si, et al. Caulophine protects cardiomyocytes from oxidative and ischemic injury. J Pharmacol Sci. 2010;113(4):368-77. DOI:10.1254/jphs.10125fp
Caulophine Preparation Products And Raw materials
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