| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
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| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:TFLLR-NH2 (trifluoroacetate salt)
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
|
| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:TFLLR-NH2 trifluoroacetate salt
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| Company Name: |
Riedel-de Haen AG
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| Tel: |
800 558-9160 |
| Email: |
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| Products Intro: |
Purity:>98% (HPLC)
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| | H-THR-PHE-LEU-LEU-ARG-NH2 TRIFLUOROACETATE SALT Basic information |
| Product Name: | H-THR-PHE-LEU-LEU-ARG-NH2 TRIFLUOROACETATE SALT | | Synonyms: | TFLLRAMIDE TRIFLUOROACETATE SALT;H-THR-PHE-LEU-LEU-ARG-NH2 TRIFLUOROACETATE SALT;L-Threonyl-L-phenylalanyl-L-leucyl-L-leucyl- L-argininamide trifluoroacetate salt;TFLLR-NH2 trifluoroacetate salt;Thr-Phe-Leu-Leu-Arg-NH2 trifluoroacetate salt | | CAS: | | | MF: | C33H54F3N9O8 | | MW: | 761.83 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File |  |
| | H-THR-PHE-LEU-LEU-ARG-NH2 TRIFLUOROACETATE SALT Chemical Properties |
| storage temp. | -20°C | | form | lyophilized powder | | color | white to tan |
| | H-THR-PHE-LEU-LEU-ARG-NH2 TRIFLUOROACETATE SALT Usage And Synthesis |
| Uses | TFLLR-NH2 trifluoroacetate salt has been used as a protease-activated receptor-1 (PAR-1) agonist to study its effects on hippocampal CA1 pyramidal neurons and Swell1 knock out mice (cKO). | | Biochem/physiol Actions | TFLLR-NH2 is a protease-activated receptor (PARs) agonist which is more selective to PAR-1 than SFLLRN-NH2. Protease-activated receptors (PARs) are present on various organs including, plateles, mast cell, gallblader, oesophagus etc, and regulate various physiological processes including human platelet aggregation, vascular contraction/relaxation, and an increase in endothelial permeability. Recent papers indicated that PAR′s are also involved in sensory processing. Specificly PAR ligands enhance glutamatergic excitatory transmission in substantia gelatinosa (SG) neurons of adult rat spinal cord slices. |
| | H-THR-PHE-LEU-LEU-ARG-NH2 TRIFLUOROACETATE SALT Preparation Products And Raw materials |
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