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[1-(3-chlorophenyl)triazol-4-yl]-thiomorpholino-methanone

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[1-(3-chlorophenyl)triazol-4-yl]-thiomorpholino-methanone Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:L524-0366
CAS:951612-19-4
Purity:98.60% Package:1mg;134USD|2mg;198USD|5mg;297USD
Company Name: TargetMol Chemicals Inc.
Tel:
Email: support@targetmol.com
Products Intro: Product Name:L524-0366；[1-(3-chlorophenyl)triazol-4-yl]-thiomorpholino-methanone
CAS:951612-19-4
Package:1 mg；10 mg；25 mg；5 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Beijing Jin Ming Biotechnology Co., Ltd.  
Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Products Intro: Product Name:(1-(3-Chlorophenyl)-1H-1,2,3-triazol-4-yl)(thiomorpholino)methanone
CAS:951612-19-4
Purity:95% Package:1g
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Products Intro: Product Name:L524-0366
CAS:951612-19-4
Purity:96.00% Package:1mg;2mg;5mg
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Products Intro: Product Name:L524-0366
CAS:951612-19-4
Purity:98.60% Package:1mg/RMB 1297;2mg/RMB 1939;5mg/RMB 2927

[1-(3-chlorophenyl)triazol-4-yl]-thiomorpholino-methanone manufacturers

  • L524-0366
  • L524-0366 pictures
  • $134.00 / 1mg
  • 2024-11-19
  • CAS:951612-19-4
  • Min. Order:
  • Purity: 98.60%
  • Supply Ability: 10g
[1-(3-chlorophenyl)triazol-4-yl]-thiomorpholino-methanone Basic information
Product Name:[1-(3-chlorophenyl)triazol-4-yl]-thiomorpholino-methanone
Synonyms:[1-(3-chlorophenyl)triazol-4-yl]-thiomorpholino-methanone;Methanone, [1-(3-chlorophenyl)-1H-1,2,3-triazol-4-yl]-4-thiomorpholinyl-;(1-(3-Chlorophenyl)-1H-1,2,3-triazol-4-yl)(thiomorpholino)methanone;L524-0366;L524 0366,L5240366,L-524-0366;L524-0366, 10 mM in DMSO
CAS:951612-19-4
MF:C13H13ClN4OS
MW:308.79
EINECS:
Product Categories:
Mol File:951612-19-4.mol
[1-(3-chlorophenyl)triazol-4-yl]-thiomorpholino-methanone Structure
[1-(3-chlorophenyl)triazol-4-yl]-thiomorpholino-methanone Chemical Properties
storage temp. -20°C (des.)
solubility Soluble in DMSO (up to 14 mg/ml with warming) or in Ethanol (up to 2 mg/ml with warming).
form solid
color Beige
Stability:Stable for 2 years from date of purchsae as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Safety Information
MSDS Information
[1-(3-chlorophenyl)triazol-4-yl]-thiomorpholino-methanone Usage And Synthesis
DescriptionL524-0366 (951612-19-4) is an Fn14 antagonist. Competes with TNF-like weak inducer of apoptosis (TWEAK) C-terminal/extracellular TNF homology domain (THD) for Fn14 binding (KD?= 7.12 μM). It specifically inhibits TWEAK-Fn14-mediated NFκB activation. L524-0366 completely suppressed TWEAK-induced T98G cell migration (10 μM) without cytotoxicity up to 50 μM.1?L524-0366 is the first compound known to interfere with the TWEAK/Fn14 interaction and may serve as a lead compound for the development of new therapeutics.2
References1) Dhruv?et al. (2013),?Structural basis and targeting of the interaction between fibroblast growth factor-inducible 14 and tumor necrosis factor-like weak inducer of apoptosis; J. Biol. Chem.,?288?32261 2) Cheng?et al. (2013),?TWEAK/Fn14 Axis-Targeted Therapeutics: Moving Basic Science Discoveries to the Clinic; Front. Immunol.,?4?473
[1-(3-chlorophenyl)triazol-4-yl]-thiomorpholino-methanone Preparation Products And Raw materials
Tag:[1-(3-chlorophenyl)triazol-4-yl]-thiomorpholino-methanone(951612-19-4) Related Product Information
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