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2-([2-(4-CHLOROPHENOXY)ETHYL]THIO)-1H-BENZIMIDAZOLE

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2-([2-(4-CHLOROPHENOXY)ETHYL]THIO)-1H-BENZIMIDAZOLE Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354
Email: support@targetmol.com
Products Intro: Product Name:CLP-3094；2-([2-(4-CHLOROPHENOXY)ETHYL]THIO)-1H-BE
CAS:312749-73-8
Package:1 mg；1 mL * 10mM (in DMSO)；10 mg；100 mg；200 mg；25 mg；5 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:CLP-3094
CAS:312749-73-8
Purity:>=95.0% Package:$143.9/5mg;$253.9/10mg;Bulk package Remarks:95.0%
Company Name: Tianjin Kailiqi Biotechnology Co., Ltd.  
Tel: 15076683720
Email: klq@cw-bio.com
Products Intro: Product Name:CLP-3094
CAS:312749-73-8
Purity:≥98% Package:1g,5g,10g,25g根据客户需要分装 Remarks:Not For Human Use, Lab Use Only.
Company Name: Yujinpharma(Tianjin) Technology Co.,Ltd.  
Tel: 13370351217 kungfu1217@1
Email: kungfu1217@163.com
Products Intro: CAS:312749-73-8
Company Name: Henan Weituxi Chemical Technology Co., Ltd.  
Tel: 0371-63284658 18135795563
Email: 2885349392@qq.com
Products Intro: CAS:312749-73-8
Purity:98% Package:100mg；500mg；1g;5g;25g
2-([2-(4-CHLOROPHENOXY)ETHYL]THIO)-1H-BENZIMIDAZOLE Basic information
Product Name:2-([2-(4-CHLOROPHENOXY)ETHYL]THIO)-1H-BENZIMIDAZOLE
Synonyms:2-([2-(4-CHLOROPHENOXY)ETHYL]THIO)-1H-BENZIMIDAZOLE;AH-034/34344061;BAS 00450541;EU-0033941;ZINC02074828;2-[2-(4-chlorophenoxy)ethylsulfanyl]-1H-benzimidazole;2-[2-(4-Chloro-phenoxy)-ethylsulfanyl]-1H-benzoimidazole;2-([2-(4-CHLOROPHENOXY)ETHYL]THIO)-1H-BE
CAS:312749-73-8
MF:C15H13ClN2OS
MW:304.79
EINECS:
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Mol File:Mol File
2-([2-(4-CHLOROPHENOXY)ETHYL]THIO)-1H-BENZIMIDAZOLE Structure
2-([2-(4-CHLOROPHENOXY)ETHYL]THIO)-1H-BENZIMIDAZOLE Chemical Properties
storage temp. RT
solubility Soluble in DMSO (up to 45 mg/ml)
form solid
color Off-white
Stability:Stable for 2 years as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
HazardClass IRRITANT
MSDS Information
2-([2-(4-CHLOROPHENOXY)ETHYL]THIO)-1H-BENZIMIDAZOLE Usage And Synthesis
DescriptionGPR142 is highly expressed in the pancreas and immune system and shares 33% homology with GPR139.1 Endogenous agonists identified to date include aromatic amino acids such as tryptophan and phenylalanine.2?CLP-3094? (312749-73-8) was identified as a potent and selective GPR142 antagonist with an IC50=2.3 μM against 1 mM L-tryptophan. It inhibited insulin secretion from islets induced by L-tryptophan and other agonists and displayed anti-inflammatory activity in a mouse arthritis model.3
ReferencesSusens et al. (2006), Characterisation and differential expression of two very closely related G-protein-coupled receptors, GPR139 and GPR142, in mouse tissue and during mouse development, Neuropharmacology, 55 512 Lizarzaburu et al. (2012), Discovery and optimization of a novel series of GPR142 agonists for the treatment of type 2 diabetes mellitus; Bioorg. Med. Chem. Lett., 22 5942 Murakoshi et al. (2017), Discovery and pharmacological effects of a novel GPR142 antagonist; Recept. Signal. Transduct. Res., 37 290
2-([2-(4-CHLOROPHENOXY)ETHYL]THIO)-1H-BENZIMIDAZOLE Preparation Products And Raw materials
Tag:2-([2-(4-CHLOROPHENOXY)ETHYL]THIO)-1H-BENZIMIDAZOLE(312749-73-8) Related Product Information
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