| Company Name: |
Key Organics Ltd.
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| Tel: |
+44 (0) 1840-212137 |
| Email: |
info@keyorganics.net |
| Products Intro: |
Product Name:(2E)-2-cyano-3-hydroxy-N-[3-(trifluoromethyl)phenyl]but-2-enamide
CAS:63927-51-5
Purity:90%
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| Company Name: |
Ryan Scientific, Inc.
|
| Tel: |
843-884-4911 x 319 |
| Email: |
ryan.reichlyn@ryansci.com |
| Products Intro: |
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| | 2-CYANO-3-HYDROXY-N-[3-(TRIFLUOROMETHYL)PHENYL]-2-BUTENAMIDE Basic information |
| | 2-CYANO-3-HYDROXY-N-[3-(TRIFLUOROMETHYL)PHENYL]-2-BUTENAMIDE Chemical Properties |
| | 2-CYANO-3-HYDROXY-N-[3-(TRIFLUOROMETHYL)PHENYL]-2-BUTENAMIDE Usage And Synthesis |
| Uses | 2-Cyano-3-hydroxy-N-[3-(trifluoromethyl)phenyl]-2-butenamide is a derivative of Leflunomide(L322750) which is an immunosuppressive. Inhibits T and B cell proliferation. Activity is attributed mainly to its metabolite, a malononitrile derivative, which is beleived to inhibit dihydroorotate dehydrogenase as well as several protein tyrosine kinases. Therapeutically as a antirheumatic (Merck Index).This compound is suitable for dihydroorotate dehydrogenase (DHODH) related research. |
| | 2-CYANO-3-HYDROXY-N-[3-(TRIFLUOROMETHYL)PHENYL]-2-BUTENAMIDE Preparation Products And Raw materials |
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