| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Email: |
marketing1@energy-chemical.com |
| Products Intro: |
Product Name:GSK269962 hydrochloride
CAS:2095432-71-4
Purity:98+% Package:10mg;25mg;50mg;5mg Remarks:NULL
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| | GSK269962 Hydrochloride Basic information |
| Product Name: | GSK269962 Hydrochloride | | Synonyms: | GSK269962 Hydrochloride;GSK269962 HCl;GSK269962A hydrochloride;N-(3-((2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl)oxy)phenyl)-4-(2-morpholinoethoxy)benzamide hydrochloride | | CAS: | 2095432-71-4 | | MF: | C29H31ClN8O5 | | MW: | 607.07 | | EINECS: | | | Product Categories: | | | Mol File: | 2095432-71-4.mol |  |
| | GSK269962 Hydrochloride Chemical Properties |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | solubility | DMSO: 100 mg/mL (164.73 mM);Ethanol: 28 mg/mL (46.12 mM) | | Water Solubility | Water: Insoluble |
| | GSK269962 Hydrochloride Usage And Synthesis |
| Biological Activity | GSK269962A HCl is a selective ROCK (Rho-associated protein kinase) inhibitor with IC50 of 1.6 nM and 4 nM for ROCK1 and ROCK2, respectively. | | target | | Target | Value | ROCK1
(Cell-free assay) | 1.6 nM | ROCK2
(Cell-free assay) | 4 nM | < td style="border-bottom: 1px dotted #ccc;padding: 5px;"> MSK1
(Cell-free assay) 49 nM | RSK1
(Cell-free assay) | 132 nM |
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| | GSK269962 Hydrochloride Preparation Products And Raw materials |
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