Company Name: |
United States Biological
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Tel: |
1-800-520-3011 |
Email: |
sales@advtechind.com |
Products Intro: |
Product Name:ZMAT4 (Zinc Finger, Matrin Type 4, FLJ13842)† APC
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| PROTEIN C Basic information |
Product Name: | PROTEIN C | Synonyms: | PROTEIN C SOLUTION;Recombinant Human Activated Protein C;4-[(4-Carboxybutyl)amino]-1-piperidinecarboxylic Acid (4S)-4,11-Diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl Ester;7-Ethyl-10-(4-N-aminopentanoic acid)-1-piperidino)carbonyloxycamptothecin;Drotrecogin Alfa;ACTIVATED HUMAN PROTEIN C;PROTEIN C, ACTIVATED, HUMAN PLASMA;PROTEIN C, HUMAN | CAS: | 60202-16-6 | MF: | C33H38N4O8 | MW: | 0 | EINECS: | | Product Categories: | enzyme;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals | Mol File: | Mol File | ![PROTEIN C Structure]() |
| PROTEIN C Chemical Properties |
Melting point | 166-168°C | storage temp. | −20°C | solubility | H2O: 1 mg/mL | form | lyophilized powder | color | Pale Yellow to Light Yellow |
Hazard Codes | B | Safety Statements | 36/37 | WGK Germany | 3 | HS Code | 3504009000 |
| PROTEIN C Usage And Synthesis |
Chemical Properties | Pale Yellow Solid | Uses | A major metabolite of Irinotecan | General Description | Drotrecogin alfa (activated), drotrecoginalfa (activated; Xigris), is a recombinant form of humanactivated protein C. Activated protein C exerts an antithromboticeffect by inhibiting factors Va and VIIIa. In vitro dataindicate that activated protein C has indirect profibrinolyticactivity through its ability to inhibit plasminogen activator inhibitor-1 (PAI-1) and to limit generation of activated thrombin-activatable fibrinolysis inhibitor. Additionally, in vitrodata indicate that activated protein C may exert an antiinflammatoryeffect by inhibiting TNF production by monocytes,by blocking leukocyte adhesion to selectins, and bylimiting the thrombin-induced inflammatory responses withinthe microvascular epithelium.Vials of drotrecogin alfa should be stored at 2°C to 8°Cwithout freezing. The reconstituted solution is stable for14 hours at 25°C. |
| PROTEIN C Preparation Products And Raw materials |
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