E3 ligase Ligand-Linker Conjugates 6 Free Base

E3 ligase Ligand-Linker Conjugates 6 Free Base Suppliers list

Company Name:	TargetMol Chemicals Inc.
Tel:	+1-781-999-5354 +1-00000000000
Email:	marketing@targetmol.com
Products Intro:	Product Name:(S,R,S)-AHPC-PEG2-NH2；VH032-PEG2-NH2;VHL Ligand-Linker Conjugates 3;E3 ligase Ligand-Linker Conjugates 6 Free Base CAS:2010159-60-9 Purity:98.00% Package:100 mg；200 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY

Company Name:	Hebei Chuanghai Biotechnology Co., Ltd
Tel:	+8615531151365
Email:	mina@chuanghaibio.com
Products Intro:	Product Name:E3 ligase Ligand-Linker Conjugates 6 Free Base CAS:2010159-60-9 Purity:99% Package:25kg

Company Name:	Jilin Chinese Academy of Sciences-yanshen Technology
Tel:	+undefined18143011203
Email:	info@chemextension.com
Products Intro:	Product Name:(S,R,S)-AHPC-PEG2-NH2 CAS:2010159-60-9 Purity:95%+ Package:1g;5g;10g;25g;50g;100g; Remarks:accept Custom Synthesis Services, support large packing

Company Name:	Xian confluore Biological Technology Co., Ltd.
Tel:	+86-15680926068 +86-15680926068
Email:	1924344760@confluore.cn
Products Intro:	Product Name:(S,R,S)-AHPC-PEG2-NH2 CAS:2010159-60-9 Purity:>98.00% Package:100mg

Company Name:	Aladdin Scientific
Tel:
Email:	tp@aladdinsci.com
Products Intro:	Product Name:(S,R. S)-AHPC-PEG2-amine hydrochloride salt CAS:2010159-60-9 Purity:98% Package:$315.9/100mg;$711.9/250mg;$1187.9/500mg;Bulk package Remarks:98%

E3 ligase Ligand-Linker Conjugates 6 Free Base manufacturers

E3 ligase Ligand-Linker Conjugates 6 Free Base Basic information

Product Name:	E3 ligase Ligand-Linker Conjugates 6 Free Base
Synonyms:	E3 ligase Ligand-Linker Conjugates 6 Free Base;(2S,4R)-1-[(2S)-2-[[2-[2-(2-aminoethoxy)ethoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide;(S,R,S)-AHPC-PEG2-NH2;VH032-PEG2-NH2;VHL Ligand-Linker Conjugates 3;PROTACs Related Compound 6;(S,R. S)-AHPC-PEG2-amine hydrochloride salt;（S,R,S)-AHPC-acetamido-O-C2-amine HCI
CAS:	2010159-60-9
MF:	C28H41N5O6S
MW:	575.73
EINECS:
Product Categories:
Mol File:	2010159-60-9.mol

E3 ligase Ligand-Linker Conjugates 6 Free Base Chemical Properties

Boiling point	856.9±65.0 °C(Predicted)
density	1.249±0.06 g/cm3(Predicted)
solubility	Soluble in Water, DMSO, Methanol
pka	13.54±0.46(Predicted)
form	Solid
color	Off-white to light yellow

Safety Information

HS Code

2934100090

MSDS Information

E3 ligase Ligand-Linker Conjugates 6 Free Base Usage And Synthesis

Description	(S, R, S)-AHPC-PEG2-amine is a synthetic PROTAC linker that incorporates an E3 ligase ligand with a PEG2 unit to empower drug research & discovery. It is reactive with NHS ester or carboxylic acid.
Uses	(S,R,S)-AHPC-PEG2-NH2 (VH032-PEG2-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs[1].
IC 50	VHL
References	[1] Chan KH, et al. Impact of Target Warhead and Linkage Vector on Inducing Protein Degradation: Comparison of Bromodomain and Extra-Terminal (BET) Degraders Derived from Triazolodiazepine (JQ1) and Tetrahydroquinoline (I-BET726) BET Inhibitor Scaffolds. J Me DOI:10.1021/acs.jmedchem.6b01912

E3 ligase Ligand-Linker Conjugates 6 Free Base Preparation Products And Raw materials

Tag:E3 ligase Ligand-Linker Conjugates 6 Free Base(2010159-60-9) Related Product Information

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