α-GalCer analog 8

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Company Name: Shanghai EFE Biological Technology Co., Ltd.  
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Products Intro: Product Name:α-Galactosylceramide Analog 8
CAS:922727-14-8
Purity:95% Package:500ug
Company Name: Shanghai Hongye Biotechnology Co. Ltd  
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Products Intro: Product Name:α-GalCer analog 8
CAS:922727-14-8
Purity:>98% Package:1mg;10mg;50mg;100mg;
Company Name: ChemeGen(Shanghai) Biotechnology Co.,Ltd.  
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Products Intro: Product Name:α-GalCer analog 8
CAS:922727-14-8
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
Company Name: TargetMol Chemicals Inc.  
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Products Intro: Product Name:α-GalCer analog 8
CAS:922727-14-8
Purity:90+%,具体纯度信息请见官网 Package:500μg/RMB 4230
Company Name: Shanghai Maclean Biochemical Technology Co., LTD  
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Products Intro: Product Name:α-GalCer analog 8 (α-Galactosylceramide analog 8)
CAS:922727-14-8
Purity:98% Package:500μg
α-GalCer analog 8 Basic information
Product Name:α-GalCer analog 8
Synonyms:α-GalCer analog 8;α-Galactosylceramide analog 8;α-GalCer analog 8;α-D-Galactopyranoside, (2S,3S,4R)-3,4-dihydroxy-2-(4-tetracosyl-1H-1,2,3-triazol-1-yl)octadecyl;α-GalCer analog 8 (α-Galactosylceramide analog 8)
CAS:922727-14-8
MF:C50H97N3O8
MW:868.34
EINECS:
Product Categories:
Mol File:922727-14-8.mol
α-GalCer analog 8 Structure
α-GalCer analog 8 Chemical Properties
Boiling point 928.8±75.0 °C(Predicted)
density 1.09±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
form A solid
pka12.92±0.70(Predicted)
Safety Information
MSDS Information
α-GalCer analog 8 Usage And Synthesis
Descriptionα-Galactosylceramide analog 8 (α-GalCer analog 8) is a triazole derivative of α-galactosylceramide.1 It increases IL-2 secretion by DN32.D3 NKT hybridoma cells when co-cultured with CD1d-transfected RBL cells pre-loaded with α-GalCer analog 8 at a concentration of 32 ng/ml. α-GalCer analog 8 (32 ng/ml) induces IL-4 secretion to a greater extent than the synthetic α-GalCer KRN 7000 in mouse splenocytes in vitro and in mouse serum following administration of a 1 μg per animal dose, indicating a Th2 response.
References1. Lee, T., Cho, M., Ko, S.-Y., et al. Synthesis and evaluation of 1,2,3-triazole containing analogues of the immunostimulant α-GalCer J. Med. Chem. 50(3),585-589(2007).
α-GalCer analog 8 Preparation Products And Raw materials
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