Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
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Tel: |
400-9205774 |
Email: |
sales@glpbio.cn |
Products Intro: |
Product Name:α-GalCer analog 8 CAS:922727-14-8 Purity:>98% Package:1mg;10mg;50mg;100mg;
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Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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Tel: |
18818260767 |
Email: |
sales@chemegen.com |
Products Intro: |
Product Name:α-GalCer analog 8 CAS:922727-14-8 Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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Company Name: |
TargetMol Chemicals Inc.
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Tel: |
4008200310 |
Email: |
marketing@tsbiochem.com |
Products Intro: |
Product Name:α-GalCer analog 8 CAS:922727-14-8 Purity:90+%,具体纯度信息请见官网 Package:500μg/RMB 4230
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Company Name: |
Shanghai Maclean Biochemical Technology Co., LTD
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Tel: |
021-50706066 15221275939 |
Email: |
shenlinxing@macklin.cn |
Products Intro: |
Product Name:α-GalCer analog 8 (α-Galactosylceramide analog 8) CAS:922727-14-8 Purity:98% Package:500μg
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| α-GalCer analog 8 Basic information |
Product Name: | α-GalCer analog 8 | Synonyms: | α-GalCer analog 8;α-Galactosylceramide analog 8;α-GalCer analog 8;α-D-Galactopyranoside, (2S,3S,4R)-3,4-dihydroxy-2-(4-tetracosyl-1H-1,2,3-triazol-1-yl)octadecyl;α-GalCer analog 8 (α-Galactosylceramide analog 8) | CAS: | 922727-14-8 | MF: | C50H97N3O8 | MW: | 868.34 | EINECS: | | Product Categories: | | Mol File: | 922727-14-8.mol | |
| α-GalCer analog 8 Chemical Properties |
Boiling point | 928.8±75.0 °C(Predicted) | density | 1.09±0.1 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble | form | A solid | pka | 12.92±0.70(Predicted) |
| α-GalCer analog 8 Usage And Synthesis |
Description | α-Galactosylceramide analog 8 (α-GalCer analog 8) is a triazole derivative of α-galactosylceramide.1 It increases IL-2 secretion by DN32.D3 NKT hybridoma cells when co-cultured with CD1d-transfected RBL cells pre-loaded with α-GalCer analog 8 at a concentration of 32 ng/ml. α-GalCer analog 8 (32 ng/ml) induces IL-4 secretion to a greater extent than the synthetic α-GalCer KRN 7000 in mouse splenocytes in vitro and in mouse serum following administration of a 1 μg per animal dose, indicating a Th2 response. | References | 1. Lee, T., Cho, M., Ko, S.-Y., et al. Synthesis and evaluation of 1,2,3-triazole containing analogues of the immunostimulant α-GalCer J. Med. Chem. 50(3),585-589(2007). |
| α-GalCer analog 8 Preparation Products And Raw materials |
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