1,2-Cyclobutanedicarboxylic acid, 3,4-diphenyl-, 1,2-bis[(1R,2R,3S,5S)-2-(methoxycarbonyl)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl] ester, (1R,2S,3R,4S)- Suppliers list
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Product Name:bis[(1R,2R,3S,5S)-2-(methoxycarbonyl)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl](1r,2c,3t,4t)-3,4-diphenylcyclobutane-1,2-dicarboxylate(β-truxilline) CAS:490-15-3 Purity:95%HPLC Package:25mg;50mg;100mg
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| 1,2-Cyclobutanedicarboxylic acid, 3,4-diphenyl-, 1,2-bis[(1R,2R,3S,5S)-2-(methoxycarbonyl)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl] ester, (1R,2S,3R,4S)- Basic information |
Product Name: | 1,2-Cyclobutanedicarboxylic acid, 3,4-diphenyl-, 1,2-bis[(1R,2R,3S,5S)-2-(methoxycarbonyl)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl] ester, (1R,2S,3R,4S)- | Synonyms: | 1,2-Cyclobutanedicarboxylic acid, 3,4-diphenyl-, 1,2-bis[(1R,2R,3S,5S)-2-(methoxycarbonyl)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl] ester, (1R,2S,3R,4S)-;β-Truxilline;bis[(1R,2R,3S,5S)-2-(methoxycarbonyl)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl](1r,2c,3t,4t)-3,4-diphenylcyclobutane-1,2-dicarboxylate(β-truxilline);Diclazuril Impurity?1 (Diclazuril EP Impurity?A) | CAS: | 490-15-3 | MF: | C38H46N2O8 | MW: | 658.78 | EINECS: | | Product Categories: | | Mol File: | 490-15-3.mol | |
| 1,2-Cyclobutanedicarboxylic acid, 3,4-diphenyl-, 1,2-bis[(1R,2R,3S,5S)-2-(methoxycarbonyl)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl] ester, (1R,2S,3R,4S)- Chemical Properties |
Melting point | Decomposes at 120°C | density | 1.29±0.1 g/cm3(Predicted) | pKa | 9.09±0.60(Predicted) |
| 1,2-Cyclobutanedicarboxylic acid, 3,4-diphenyl-, 1,2-bis[(1R,2R,3S,5S)-2-(methoxycarbonyl)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl] ester, (1R,2S,3R,4S)- Usage And Synthesis |
Description | This isomeric alkaloid from the leaf extract of Erythroxylon truxillense Rusby
sinters at 45°C and decomposes above 120°C. It is laevorotatory with [α]D -
29.3°. On acid hydrolysis it yields MeOH, (-)-ecgonine and {3-truxillic acid, m.p.
206°C and may be synthesized in a similar manner to the preceding base. | Uses | β-Truxilline is an alkaloid found in coca leaves. It is an impurity of illicit Cocaine (C633500), which inhibits the dopamine, norepinephrine, and serotonin transporters. | References | Hesse., Pharm. Zeit., 407,668 (1887)
Liebermann., Ber., 21,2342 (1888)
Hesse., ibid, 22,665 (1889)
Liebermann, Drory., ibid, 22,682 (1889) |
| 1,2-Cyclobutanedicarboxylic acid, 3,4-diphenyl-, 1,2-bis[(1R,2R,3S,5S)-2-(methoxycarbonyl)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl] ester, (1R,2S,3R,4S)- Preparation Products And Raw materials |
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