-triphosphate, Triethylammonium Salt) (1mM)
| 中文名称 | -triphosphate, Triethylammonium Salt) (1mM) |
|---|---|
| 中文同义词 | |
| 英文名称 | -triphosphate, Triethylammonium Salt) (1mM) |
| 英文同义词 | 11-dUTP (Biotin) (g-[N-(Biotin-6-amino-hexanoyl)]-5-aminoallyl-2’-deoxy-uridine-5’-triphosphate, Triethylammonium Salt) (1mM);4-dUTP (Biotin) (N-Biotin-5-(3-aminoallyl)-2’16-dUTP (Biotin) g-[N-(Biotin-6-amino-hexanoyl-6-aminobutanoyl)]-5-(3-aminoallyl)-2’3'-Deoxyuridine-5'-triphosphate;3'Deoxyuridine5'triphosphate,3' Deoxyuridine 5' triphosphate;Uridine 5'-(tetrahydrogen triphosphate), 3'-deoxy- |
| CAS号 | 69199-40-2 |
| 分子式 | C9H15N2O14P3 |
| 分子量 | 468.14 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 69199-40-2.mol |
| 结构式 |  |
-triphosphate, Triethylammonium Salt) (1mM) 性质
| 密度 | 2.010±0.06 g/cm3(Predicted) |
|---|---|
| 酸度系数(pKa) | 0.80±0.50(Predicted) |
3'-Deoxyuridine-5'-triphosphate (3'-dUTP) 是一种核苷酸类似物，可抑制 DNA 依赖性 RNA 聚合酶 I 和 II (RNA polymerases I 和 II)，强烈并竞争性地抑制 UTP 掺入到 RNA 中，Ki 值为 2.0 μM。
3'-Deoxyuridine-5'-triphosphate (3'-dUTP) is synthesized starting from cordycepin in good yield. 3'-Deoxyuridine-5'-triphosphate strongly and competitively inhibits the incorporations of UTP into RNA by the RNA polymerases. 3'-Deoxyuridine-5'-triphosphate will be useful in studies at the molecular level on the relationship of template and substrate in RNA synthesis with chromatin, isolated nuclei or permeable cells, because it does not have any effect on poly (rA) synthesis.
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2023/03/20 | HY-135780 | -triphosphate, Triethylammonium Salt) (1mM) 3'-Deoxyuridine-5'-triphosphate | 69199-40-2 | 1mg | 22000元 |