| Company Name: |
Amatek Scientific Co. Ltd.
|
| Tel: |
0512-56316828 |
| Email: |
info@amateksci.com |
| Products Intro: |
Product Name:N3-PEG7-CH2COOH
CAS:1446411-32-0
Purity:97% HPLC Package:1g;5g;25g;100g
|
|
| | Azido-PEG7-acid Basic information |
| | Azido-PEG7-acid Chemical Properties |
| | Azido-PEG7-acid Usage And Synthesis |
| Biological Activity | Azido-PEG7-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | Azido-PEG7-acid Preparation Products And Raw materials |
|