Prostaglandin D Synthase (hematopoietic-type) Inhibitor F092

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Products Intro: Product Name:Prostaglandin D Synthase (hematopoietic-type) Inhibitor F092
CAS:2250261-59-5
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Products Intro: Product Name:Prostaglandin D Synthase (hematopoietic-type) Inhibitor F092
CAS:2250261-59-5
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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CAS:2250261-59-5
Purity:>98% Package:mg
Prostaglandin D Synthase (hematopoietic-type) Inhibitor F092 Basic information
Product Name:Prostaglandin D Synthase (hematopoietic-type) Inhibitor F092
Synonyms:Prostaglandin D Synthase (hematopoietic-type) Inhibitor F092;F092 inhibitor;5-Pyrimidinecarboxamide, N-[4-(2-oxo-1-pyrrolidinyl)phenyl]-2-(2-pyridinyl)-;N-[4-(2-oxo-1-pyrrolidinyl)phenyl]-2-(2-pyridinyl)-5-pyrimidinecarboxamide;F092
CAS:2250261-59-5
MF:C20H17N5O2
MW:359.38
EINECS:
Product Categories:
Mol File:2250261-59-5.mol
Prostaglandin D Synthase (hematopoietic-type) Inhibitor F092 Structure
Prostaglandin D Synthase (hematopoietic-type) Inhibitor F092 Chemical Properties
Boiling point 509.0±48.0 °C(Predicted)
density 1.359±0.06 g/cm3(Predicted)
solubility DMF: 3 mg/ml; DMSO: 5 mg/ml; Ethanol: partially soluble; PBS (pH 7.2): partially soluble
form A crystalline solid
pka10.70±0.70(Predicted)
color White to off-white
Safety Information
MSDS Information
Prostaglandin D Synthase (hematopoietic-type) Inhibitor F092 Usage And Synthesis
DescriptionProstaglandin D synthase (hematopoietic-type) inhibitor F092 is an inhibitor of hematopoietic-type prostaglandin D synthase (H-PGDS; KD = 0.14 nM).1
References1. Takaya, D., Inaka, K., Omura, A., et al. Characterization of crystal water molecules in a high-affinity inhibitor and hematopoietic prostaglandin D synthase complex by interaction energy studies Bioorg. Med. Chem. 26(16),4726-4734(2018).
Prostaglandin D Synthase (hematopoietic-type) Inhibitor F092 Preparation Products And Raw materials
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