| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:CAY10742
CAS:1649473-91-5
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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CAY10742 manufacturers
- CAY10742
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- $110.00 / 1mg
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2024-10-28
- CAS:1649473-91-5
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | CAY10742 Basic information |
| Product Name: | CAY10742 | | Synonyms: | CAY10742;1H-Indole, 5-[3-[4-(4-fluorophenoxy)phenyl]-1,2,4-oxadiazol-5-yl]-;5-[3-[4-(4-fluorophenoxy)phenyl]-1,2,4-oxadiazol-5-yl]-1H-indole | | CAS: | 1649473-91-5 | | MF: | C22H14FN3O2 | | MW: | 371.36 | | EINECS: | | | Product Categories: | | | Mol File: | 1649473-91-5.mol |  |
| | CAY10742 Chemical Properties |
| Boiling point | 574.8±60.0 °C(Predicted) | | density | 1.343±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 11mg/mL,DMF:PBS (pH 7.2) (1:2): 0.3mg/mL,DMSO: 10mg/mL | | form | A crystalline solid | | pka | 15.67±0.30(Predicted) |
| | CAY10742 Usage And Synthesis |
| Biological Activity | CAY10742 is an orally bioavailable oxadiazole antibiotic.1 It is active against the Gram-positive bacteria S. aureus, S. epidermidis, S. haemolyticus, B. cereus, B. licheniformis, E. faecalis, and E. faecium (MICs = 1-4 μg/ml), including laboratory strains and clinical isolates with varying degrees of resistance to methicillin, vancomycin, linezolid, and other antibiotics. CAY10742 (40 mg/kg) reduces the number of bacteria in mouse neutropenic thigh models of linezolid-sensitive or -resistant methicillin-resistant S. aureus (MRSA) infection. | | References | 1.Boudreau, M.A., Ding, D., Meisel, J.E., et al.Structure-activity relationship for the oxadiazole class of antibacterialsMed. Chem. Lett.11(3)322-326(2019) |
| | CAY10742 Preparation Products And Raw materials |
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