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Product Name:tert-Butyl (47-amino-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45-pentadecaoxaheptatetracontyl)carbamate CAS:2222566-55-2 Purity:95%+ Package:1g;5g;10g;25g;50g;100g; Remarks:accept Custom Synthesis Services, support large packing
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T&W GROUP
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Product Name:Boc-NH-PEG15-NH2 CAS:2222566-55-2 Purity:98% Package:按需包装
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Boc-NH-PEG15-NH2 manufacturers
- Boc-NH-PEG15-NH2
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- $68.00 / 2mg
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2024-10-28
- CAS:2222566-55-2
- Min. Order:
- Purity:
- Supply Ability: 10g
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| Boc-NH-PEG15-NH2 Basic information |
Product Name: | Boc-NH-PEG15-NH2 | Synonyms: | Boc-NH-PEG15-NH2;t-Boc-Amido-PEG16-Amine;BocNH-PEG15-CH2CH2NH2/5,8,11,14,17,20,23,26,29,32,35,38,41,44,47-Pentadecaoxa-2-azanonatetracontanoic acid, 49-amino-, 1,1-dimethylethyl ester;5,8,11,14,17,20,23,26,29,32,35,38,41,44,47-Pentadecaoxa-2-azanonatetracontanoic acid, 49-amino-, 1,1-dimethylethyl ester;tert-Butyl (47-amino-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45-pentadecaoxaheptatetracontyl)carbamate | CAS: | 2222566-55-2 | MF: | C37H76N2O17 | MW: | 821 | EINECS: | | Product Categories: | | Mol File: | 2222566-55-2.mol | |
| Boc-NH-PEG15-NH2 Chemical Properties |
Boiling point | 773.0±60.0 °C(Predicted) | density | 1.093±0.06 g/cm3(Predicted) | pka | 12.23±0.46(Predicted) | form | Oil | color | Colorless to off-white |
| Boc-NH-PEG15-NH2 Usage And Synthesis |
Biological Activity | Boc-NH-PEG15-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| Boc-NH-PEG15-NH2 Preparation Products And Raw materials |
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