| Company Name: |
Nanjing Shizhou Biology Technology Co.,Ltd
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| Tel: |
025-85563444 18351873721 |
| Email: |
purchase@synzest.com |
| Products Intro: |
Product Name:Methoxy-Tr-NH-PEG7
CAS:2353409-88-6
Purity:95%HPLC Package:50mg;100mg;250mg;1g
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| Company Name: |
Zhengzhou Akem Chemical Co., Ltd
|
| Tel: |
13303867194 |
| Email: |
3001317055@qq.com |
| Products Intro: |
Product Name:(4-methoxyphenyl)diphenylmethylamino-PEG7
CAS:2353409-88-6
Purity:95% Package:100mg；250mg；1g；
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| | Methoxy-Tr-NH-PEG7 Basic information |
| Product Name: | Methoxy-Tr-NH-PEG7 | | Synonyms: | Methoxy-Tr-NH-PEG7;(4-methoxyphenyl)diphenylmethylamino-PEG7;3,6,9,12,15,18-Hexaoxa-21-azadocosan-1-ol, 22-(4-methoxyphenyl)-22,22-diphenyl- | | CAS: | 2353409-88-6 | | MF: | C34H47NO8 | | MW: | 597.74 | | EINECS: | | | Product Categories: | | | Mol File: | 2353409-88-6.mol |  |
| | Methoxy-Tr-NH-PEG7 Chemical Properties |
| Boiling point | 697.3±55.0 °C(Predicted) | | density | 1.122±0.06 g/cm3(Predicted) | | pka | 14.36±0.10(Predicted) |
| | Methoxy-Tr-NH-PEG7 Usage And Synthesis |
| Biological Activity | Methoxy-Tr-NH-PEG7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | Methoxy-Tr-NH-PEG7 Preparation Products And Raw materials |
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