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| Methanone, (2,6-dimethoxyphenyl)[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]- Basic information |
Product Name: | Methanone, (2,6-dimethoxyphenyl)[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]- | Synonyms: | Methanone, (2,6-dimethoxyphenyl)[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]-;MUN57694;26S proteasome inhibitor I;Proteasome,Inhibitor,inhibit,MUN57694,MUN-57694;(2,6-Dimethoxyphenyl)[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]methanone | CAS: | 858557-69-4 | MF: | C23H25N3O4 | MW: | 407.46 | EINECS: | | Product Categories: | | Mol File: | 858557-69-4.mol | |
| Methanone, (2,6-dimethoxyphenyl)[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]- Chemical Properties |
Boiling point | 621.2±65.0 °C(Predicted) | density | 1?+-.0.06 g/cm3(Predicted) | storage temp. | 4°C, protect from light | solubility | DMSO : 31.25 mg/mL (76.69 mM; ultrasonic and warming and heat to 60°C) | form | Solid | pka | -0.58±0.44(Predicted) | color | White to off-white |
| Methanone, (2,6-dimethoxyphenyl)[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]- Usage And Synthesis |
Biological Activity | 20S Proteasome-IN-1 is a 26S proteasome inhibitor extracted from patent WO2006128196A2 compound 2. 20S Proteasome-IN-1 has the potential for cancer, immune-related disorders, inflammation, ischemic conditions, neurodegenerative disorders and other diseases research[1]. | References | [1]. Parlati F, et, al. Novel substrate for rpn 11 enzymatic activity. WO2006128196A2. |
| Methanone, (2,6-dimethoxyphenyl)[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]- Preparation Products And Raw materials |
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