4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate
生物活性体内研究 用途与合成方法 MSDS 4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate价格(试剂级) 上下游产品信息
| 中文名称 | 4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate |
|---|---|
| 中文同义词 | 化合物 T10355;化合物APYRAMIDE |
| 英文名称 | 4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate |
| 英文同义词 | 4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate;apyramide;1-(4-Chlorobenzoyl)-2-methyl-5-methoxy-1H-indole-3-acetic acid 4-(acetylamino)phenyl ester;1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid 4-(acetylamino)phenyl ester;1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 4-(acetylamino)phenyl ester |
| CAS号 | 68483-33-0 |
| 分子式 | C27H23ClN2O5 |
| 分子量 | 490.93 |
| EINECS号 | 2709139 |
| 相关类别 | |
| Mol文件 | 68483-33-0.mol |
| 结构式 |  |
4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate 性质
| 熔点 | 145-150 °C(Solv: benzene (71-43-2); methanol (67-56-1)) |
|---|---|
| 沸点 | 671.1±55.0 °C(Predicted) |
| 密度 | 1.29±0.1 g/cm3(Predicted) |
| 储存条件 | Store at -20°C |
| 溶解度 | 溶于二甲基亚砜 |
| 酸度系数(pKa) | 14.20±0.70(Predicted) |
Apyramide 是一种抗炎试剂 (NSAID)，是吲哚美辛 (HY-14397) 的前药。Indomethacin 是一种强效的、血脑通透的、非选择性的 COX1 和 COX2 抑制剂。
Apyramide is far less toxic than indomethacin in rats and mice by the oral or the i.p. route. It exhibits anti-inflammatory activity on carrageenin-induced paw oedema, cotton pellet granuloma and adjuvant arthritis, as well as analgesic and antipyretic activities.
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/04/30 | HY-U00046 | 4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate Apyramide | 68483-33-0 | 5mg | 2000元 |
| 2024/04/30 | HY-U00046 | 4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate Apyramide | 68483-33-0 | 10mg | 3400元 |