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Tetrazolo[1,5-a]pyrimidine-6-carboxamide, 4,7-dihydro-4,5,7,7-tetramethyl-N-(3-phenyl-1H-indazol-5-yl)-

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Tetrazolo[1,5-a]pyrimidine-6-carboxamide, 4,7-dihydro-4,5,7,7-tetramethyl-N-(3-phenyl-1H-indazol-5-yl)- Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:EB-42486
CAS:2390475-81-5
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
Company Name: Finetech Industry Limited
Tel: +86-27-87465837 +8618971612321
Email: info@finetechnology-ind.com
Products Intro: Product Name:4,5,7,7-tetramethyl-N-(3-phenyl-1H-indazol-5-yl)tetrazolo[1,5-a]pyrimidine-6-carboxamide
CAS:2390475-81-5
Purity:98% Package:1g,5g,25g,500g,1kg
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354
Email: support@targetmol.com
Products Intro: Product Name:EB-42486
CAS:2390475-81-5
Package:1 mg；1 mL * 10mM (in DMSO)；10 mg；100 mg；25 mg；5 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:EB-42486
CAS:2390475-81-5
Purity:99% Package:$380.9/5mg;$600.9/10mg;$1150.9/25mg;Bulk package Remarks:99%
Company Name: Finetech Industry Limited  
Tel: 027-87465837 19945049750
Email: sales@finetechnology-ind.com
Products Intro: Product Name:4,5,7,7-tetramethyl-N-(3-phenyl-1H-indazol-5-yl)tetrazolo[1,5-a]pyrimidine-6-carboxamide
CAS:2390475-81-5
Purity:98% Package:1g,5g,25g,500g,1kg
Tetrazolo[1,5-a]pyrimidine-6-carboxamide, 4,7-dihydro-4,5,7,7-tetramethyl-N-(3-phenyl-1H-indazol-5-yl)- Basic information
Product Name:Tetrazolo[1,5-a]pyrimidine-6-carboxamide, 4,7-dihydro-4,5,7,7-tetramethyl-N-(3-phenyl-1H-indazol-5-yl)-
Synonyms:Tetrazolo[1,5-a]pyrimidine-6-carboxamide, 4,7-dihydro-4,5,7,7-tetramethyl-N-(3-phenyl-1H-indazol-5-yl)-;EB-42486;EB-42486,EB 42486,inhibit,EB42486,Inhibitor,LRRK2,Leucine-rich repeat kinase 2;4,5,7,7-tetramethyl-N-(3-phenyl-1H-indazol-5-yl)tetrazolo[1,5-a]pyrimidine-6-carboxamide;4,5,7,7-Tetramethyl-N-(3-phenyl-1H-indazol-5-yl)-4,7-dihydrotetrazolo[1,5-a]pyrimidine-6-carboxamide
CAS:2390475-81-5
MF:C22H22N8O
MW:414.46
EINECS:
Product Categories:
Mol File:2390475-81-5.mol
Tetrazolo[1,5-a]pyrimidine-6-carboxamide, 4,7-dihydro-4,5,7,7-tetramethyl-N-(3-phenyl-1H-indazol-5-yl)- Structure
Tetrazolo[1,5-a]pyrimidine-6-carboxamide, 4,7-dihydro-4,5,7,7-tetramethyl-N-(3-phenyl-1H-indazol-5-yl)- Chemical Properties
density 1.41±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 250 mg/mL (603.19 mM; Need ultrasonic)
form Solid
pka11.92±0.40(Predicted)
color Off-white to light yellow
Safety Information
MSDS Information
Tetrazolo[1,5-a]pyrimidine-6-carboxamide, 4,7-dihydro-4,5,7,7-tetramethyl-N-(3-phenyl-1H-indazol-5-yl)- Usage And Synthesis
Biological ActivityEB-42486 is a novel, potent, and highly selective G2019S-LRRK2 inhibitor (IC50 < 0.2 nM).
References[1]. Garofalo AW, et al. Selective Inhibitors of G2019S-LRRK2 Kinase Activity. J Med Chem. 2020 Dec 10;63(23):14821-14839.
Tetrazolo[1,5-a]pyrimidine-6-carboxamide, 4,7-dihydro-4,5,7,7-tetramethyl-N-(3-phenyl-1H-indazol-5-yl)- Preparation Products And Raw materials
Tag:Tetrazolo[1,5-a]pyrimidine-6-carboxamide, 4,7-dihydro-4,5,7,7-tetramethyl-N-(3-phenyl-1H-indazol-5-yl)-(2390475-81-5) Related Product Information