| Company Name: |
ShangHai Caerulum Pharma Discovery Co., Ltd.
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| Tel: |
18149758185 18149758185 |
| Email: |
sales-cpd@caerulumpharma.com |
| Products Intro: |
Product Name:N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-6-((1-(19-((4R)-4-hydroxy-2-((1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidine-1-carbonyl)-20,20-dimethyl-17-oxo-3,6,9,12,15-pentaoxa-18-azahenicosanoyl)azetidin-3-yl)amino)pyrimidine-4-carboxamide
CAS:2375432-47-4
Purity:98% Package:1g;10g;100g
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| Company Name: |
Zhengzhou anmousse chemical products co. LTD
|
| Tel: |
0371-55289822 18737195735 |
| Email: |
483339295@qq.com |
| Products Intro: |
Product Name:INDEX NAME NOT YET ASSIGNED
CAS:2375432-47-4
Purity:98% Package:5g;10g;25g;50g;100g
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| | INDEX NAME NOT YET ASSIGNED Basic information |
| Product Name: | INDEX NAME NOT YET ASSIGNED | | Synonyms: | N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-6-((1-(19-((4R)-4-hydroxy-2-((1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidine-1-carbonyl)-20,20-dimethyl-17-oxo-3,6,9,12,15-pentaoxa-18-azahenicosanoyl)azetidin-3-yl)amino)pyrimidine-4-carboxamide;6-{[1-(1-{[(2S)-1-[(2S,4R)-4-hydroxy-2-{[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]carbamoyl}pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]carbamoyl}-2,5,8,11,14-pentaoxahexadecanoyl)azetidin-3-yl]amino}-N-[(2S)-2-hydroxy-3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propyl]pyrimidine-4-carboxamide | | CAS: | 2375432-47-4 | | MF: | C55H76N10O12S | | MW: | 1101.33 | | EINECS: | | | Product Categories: | | | Mol File: | 2375432-47-4.mol |  |
| | INDEX NAME NOT YET ASSIGNED Chemical Properties |
| Boiling point | 1254.3±65.0 °C(Predicted) | | density | 1.295±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : 100 mg/mL (90.80 mM; Need ultrasonic) | | form | Solid | | pka | 12.41±0.46(Predicted) | | color | White to light yellow |
| | INDEX NAME NOT YET ASSIGNED Usage And Synthesis |
| Biological Activity | MS4322 (YS43-22) is a first-in-class PRMT5 degrader and a valuable chemical tool (PROTAC) for exploring the PRMT5 functions in health and disease. | | References | [1]. Shen Y, et al. Discovery of First-in-Class Protein Arginine Methyltransferase 5 (PRMT5) Degraders. J Med Chem. 2020 Sep 10;63(17):9977-9989. |
| | INDEX NAME NOT YET ASSIGNED Preparation Products And Raw materials |
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