| Company Name: |
Shanghai Raise Chemical Technology Co.,Ltd
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| Tel: |
15026594951 |
| Email: |
rs@raise-chem.com |
| Products Intro: |
Product Name:N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamido)-2-methylphenyl)-2-methylquinoline-6-carboxamide
CAS:1693731-14-4
Purity:97% HPLC Package:1g;5g
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| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:CCT245232
CAS:1693731-14-4
Purity:98% Package:200 mg
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| Company Name: |
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd
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| Tel: |
021-59167510 18117107507 |
| Email: |
vip@med-life.cn |
| Products Intro: |
Product Name:CCT245232
CAS:1693731-14-4
Purity:>=99% Package:500mg;25mg;10mM*1mLinDMSO;100mg;50mg;10mg;5mg;200mg
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| Company Name: |
RD International Technology Co., Limited
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| Tel: |
18024082417 |
| Email: |
market@ubiochem.com |
| Products Intro: |
Product Name:JG-231
CAS:1693731-14-4
Purity:5mg;10mg;50mg;100mg;250mg;500mg;1g Package:5mg;10mg;50mg;100mg;250mg;500mg;1g
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| | 6-Quinolinecarboxamide, N-[5-[[(2,3-dihydro-1,4-benzodioxin-6-yl)carbonyl]amino]-2-methylphenyl]-2-methyl- Basic information |
| | 6-Quinolinecarboxamide, N-[5-[[(2,3-dihydro-1,4-benzodioxin-6-yl)carbonyl]amino]-2-methylphenyl]-2-methyl- Chemical Properties |
| Boiling point | 535.5±50.0 °C(Predicted) | | density | 1.349±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : 41.67 mg/mL (91.89 mM; ultrasonic and warming and heat to 60°C) | | pka | 12.49±0.70(Predicted) | | form | Solid | | color | Off-white to light brown |
| | 6-Quinolinecarboxamide, N-[5-[[(2,3-dihydro-1,4-benzodioxin-6-yl)carbonyl]amino]-2-methylphenyl]-2-methyl- Usage And Synthesis |
| Biological Activity | CCT245232 is a potent inhibitor of heat shock factor 1 (HSF1). HSF1 is the master regulator of the heat shock response, in which multiple genes are induced in response to temperature increase and other stresses. CCT245232 has the potential for the research of proliferative diseases, such as cancer (extracted from patent WO2015049535A1)[1]. | | References | [1]. Keith Jones, et al. Fused 1,4-dihydrodioxin derivatives as inhibitors of heat shock transcription factor 1. Patent WO2015049535A1. |
| | 6-Quinolinecarboxamide, N-[5-[[(2,3-dihydro-1,4-benzodioxin-6-yl)carbonyl]amino]-2-methylphenyl]-2-methyl- Preparation Products And Raw materials |
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