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2,5-Piperazinedione, 3,6-bis[4-[bis[(9Z,12Z)-2-hydroxy-9,12-octadecadien-1-yl]amino]butyl]-

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2,5-Piperazinedione, 3,6-bis[4-[bis[(9Z,12Z)-2-hydroxy-9,12-octadecadien-1-yl]amino]butyl]- Suppliers list
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:OF-02
CAS:1883431-67-1
Purity:>=98.0% Package:$510.9/5mg;$800.9/10mg;$1600.9/25mg;Bulk package Remarks:98.0%
Company Name: Shanghai EFE Biological Technology Co., Ltd.  
Tel: 021-65675885 18964387627
Email: info@efebio.com
Products Intro: Product Name:OF-02
CAS:1883431-67-1
Purity:95% Package:1mg;5mg;10mg
Company Name: Shanghai Changyu Medical Technology Co. Ltd.  
Tel: +86-13301875428
Email: sales@changyuhe.com
Products Intro: CAS:1883431-67-1
Purity:98% Package:1mg;5mg
Company Name: Shenzhen Polymeri Biochemical Technology Co., Ltd.  
Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Products Intro: CAS:1883431-67-1
Purity:>=95% Remarks:1mg\g\kg\ton
Company Name: Shochem(Shanghai)Co.,Ltd  
Tel: +86-021-51783479 +86-13816874662
Email: info@shochem.com
Products Intro: Product Name:2,5-Piperazinedione, 3,6-bis[4-[bis[(9Z,12Z)-2-hydroxy-9,12-octadecadien-1-yl]amino]butyl]-;OF-02
CAS:1883431-67-1
Purity:98% Package:1g;10g;100g
2,5-Piperazinedione, 3,6-bis[4-[bis[(9Z,12Z)-2-hydroxy-9,12-octadecadien-1-yl]amino]butyl]- Basic information
Product Name:2,5-Piperazinedione, 3,6-bis[4-[bis[(9Z,12Z)-2-hydroxy-9,12-octadecadien-1-yl]amino]butyl]-
Synonyms:2,5-Piperazinedione, 3,6-bis[4-[bis[(9Z,12Z)-2-hydroxy-9,12-octadecadien-1-yl]amino]butyl]-;OF-02;3,6-Bis(4-(bis((9Z,12Z)-2-hydroxyoctadeca-9,12-dien-1-yl)amino)butyl)piperazine-2,5-dione
CAS:1883431-67-1
MF:C84H152N4O6
MW:1314.13
EINECS:
Product Categories:
Mol File:1883431-67-1.mol
2,5-Piperazinedione, 3,6-bis[4-[bis[(9Z,12Z)-2-hydroxy-9,12-octadecadien-1-yl]amino]butyl]- Structure
2,5-Piperazinedione, 3,6-bis[4-[bis[(9Z,12Z)-2-hydroxy-9,12-octadecadien-1-yl]amino]butyl]- Chemical Properties
Boiling point 1159.0±65.0 °C(Predicted)
density 0.954±0.06 g/cm3(Predicted)
solubility Ethanol: 10 mg/ml
form Oil
pka12.87±0.60(Predicted)
color Colorless to light yellow
Safety Information
MSDS Information
2,5-Piperazinedione, 3,6-bis[4-[bis[(9Z,12Z)-2-hydroxy-9,12-octadecadien-1-yl]amino]butyl]- Usage And Synthesis
DescriptionOF-02 is an ionizable cationic amino lipid that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA.1 LNPs containing OF-02 localize to the liver after intravenous administration in mice. Intravenous administration of LNPs containing OF-02 and encapsulating human erythropoietin (EPO) mRNA increases serum EPO levels in mice.
References1. Fenton, O.S., Kauffman, K.J., McClellan, R.L., et al. Bioinspired alkenyl amino alcohol ionizable lipid materials for highly potent in vivo mRNA delivery Adv. Mater. 28(15),2939-2943(2016).
2,5-Piperazinedione, 3,6-bis[4-[bis[(9Z,12Z)-2-hydroxy-9,12-octadecadien-1-yl]amino]butyl]- Preparation Products And Raw materials
Tag:2,5-Piperazinedione, 3,6-bis[4-[bis[(9Z,12Z)-2-hydroxy-9,12-octadecadien-1-yl]amino]butyl]-(1883431-67-1) Related Product Information