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2-Pyrimidinamine, N-[4-(1-methylethyl)phenyl]-4-pyrazolo[1,5-b]pyridazin-3-yl-

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2-Pyrimidinamine, N-[4-(1-methylethyl)phenyl]-4-pyrazolo[1,5-b]pyridazin-3-yl- Suppliers list
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Products Intro: Product Name:UNC10112785
CAS:748142-06-5
Purity:98% Package:5mg;10mg;25mg
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Products Intro: Product Name:UNC10112785
CAS:748142-06-5
Purity:0 Package:25mg/RMB 10600;50mg/RMB 13800;100mg/RMB 17500
2-Pyrimidinamine, N-[4-(1-methylethyl)phenyl]-4-pyrazolo[1,5-b]pyridazin-3-yl- Basic information
Product Name:2-Pyrimidinamine, N-[4-(1-methylethyl)phenyl]-4-pyrazolo[1,5-b]pyridazin-3-yl-
Synonyms:2-Pyrimidinamine, N-[4-(1-methylethyl)phenyl]-4-pyrazolo[1,5-b]pyridazin-3-yl-
CAS:748142-06-5
MF:C19H18N6
MW:330.39
EINECS:
Product Categories:
Mol File:748142-06-5.mol
2-Pyrimidinamine, N-[4-(1-methylethyl)phenyl]-4-pyrazolo[1,5-b]pyridazin-3-yl- Structure
2-Pyrimidinamine, N-[4-(1-methylethyl)phenyl]-4-pyrazolo[1,5-b]pyridazin-3-yl- Chemical Properties
density 1.28±0.1 g/cm3(Predicted)
pka2.13±0.10(Predicted)
Safety Information
MSDS Information
2-Pyrimidinamine, N-[4-(1-methylethyl)phenyl]-4-pyrazolo[1,5-b]pyridazin-3-yl- Usage And Synthesis
DescriptionUNC10112785 is a novel potent inhibitor of CDK8, CDK19, and CDK9 with IC50 at 1.05, 2.67, and 19.9 nM, respectively, causing MYC loss through both transcriptional and posttranslational mechanisms, and suppressing PDAC anchorage-dependent and anchorage-independent growth, inducing the substantial loss of MYC protein in both two-dimensional (2D) and 3D cell cultures.
2-Pyrimidinamine, N-[4-(1-methylethyl)phenyl]-4-pyrazolo[1,5-b]pyridazin-3-yl- Preparation Products And Raw materials
Tag:2-Pyrimidinamine, N-[4-(1-methylethyl)phenyl]-4-pyrazolo[1,5-b]pyridazin-3-yl-(748142-06-5) Related Product Information