| Company Name: |
Tianjin Kailiqi Biotechnology Co., Ltd.
|
| Tel: |
15076683720 |
| Email: |
klq@cw-bio.com |
| Products Intro: |
Product Name:BPN15477
CAS:1971086-99-3
Purity:大于98% Package:1g,5g,10g,25g根据客户需要分装 Remarks:Not For Human Use, Lab Use Only.
|
| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
|
| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:BPN-15477
CAS:1971086-99-3
Purity:95.00% Package:2mg;5mg;1mL
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:BPN-15477
CAS:1971086-99-3
Package:2mg/RMB 497;5mg/RMB 869
|
BPN-15477 manufacturers
- BPN-15477
-
- $58.00 / 2mg
-
2024-10-28
- CAS:1971086-99-3
- Min. Order:
- Purity:
- Supply Ability: 10g
|
| | BPN-15477 Basic information |
| Product Name: | BPN-15477 | | Synonyms: | BPN-15477;7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 2-chloro-N-(4-pyridinylmethyl)- | | CAS: | 1971086-99-3 | | MF: | C12H10ClN5 | | MW: | 259.69 | | EINECS: | | | Product Categories: | | | Mol File: | 1971086-99-3.mol |  |
| | BPN-15477 Chemical Properties |
| density | 1.495±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | form | Solid | | pka | 11.97±0.50(Predicted) | | color | White to light yellow |
| | BPN-15477 Usage And Synthesis |
| Biological Activity | BPN-15477 is a potent SMC (splicing modulator compound) that restores correct splicing of ELP1 (Elongator complex protein 1) exon 20. BPN-15477 corrects splicing of the ELP1 transcript, significantly increases the level of functional protein in vivo in all tissues, including brain. BPN-15477 can be used for frontotemporal dementia research[1]. | | References | [1]. Gao D, et al. A deep learning approach to identify gene targets of a therapeutic for human splicing disorders. Nat Commun. 2021 Jun 7;12(1):3332. |
| | BPN-15477 Preparation Products And Raw materials |
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