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Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:GFB-12811
CAS:2775311-17-4
Purity:98% Package:$950.9/5mg;$1500.9/10mg;Bulk package Remarks:98%
INDEX NAME NOT YET ASSIGNED Basic information
Product Name:INDEX NAME NOT YET ASSIGNED
Synonyms:
CAS:2775311-17-4
MF:C22H23F4N5O
MW:449.44
EINECS:
Product Categories:
Mol File:Mol File
INDEX NAME NOT YET ASSIGNED Structure
INDEX NAME NOT YET ASSIGNED Chemical Properties
Boiling point 518.5±50.0 °C(Predicted)
density 1.369±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
pka12.94±0.29(Predicted)
Safety Information
MSDS Information
INDEX NAME NOT YET ASSIGNED Usage And Synthesis
Biological ActivityGFB-12811 is a high selective and orally active CDK5 inhibitor with an IC50 of 2.3 nM. GFB-12811 is highly selective over the other tested kinases (CDK1/2/6/7/9)[1].
References[1]. Daniels MH, et al. Discovery and Optimization of Highly Selective Inhibitors of CDK5. J Med Chem. 2022;65(4):3575-3596.
INDEX NAME NOT YET ASSIGNED Preparation Products And Raw materials
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