(1S,3S)-1-氨基-1,3-环戊烷二甲酸
中文名称 | (1S,3S)-1-氨基-1,3-环戊烷二甲酸 |
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中文同义词 | (1S,3S)-1-氨基-1,3-环戊烷二甲酸 |
英文名称 | (±)-trans-1-amino-1,3-dicarboxycyclopentane |
英文同义词 | (±)-trans-1-amino-1,3-dicarboxycyclopentane;(±)-trans-1-Amino-1,3-dicarboxycyclopentane, cis-ACPD, (±)-trans-1-Aminocyclopentane-1,3-dicarboxylic acid (according to CAS(R), IUPAC);(±)-trans-1-Aminocyclopentane-1,3-dicarboxylic acid (according to CAS?, IUPAC);1,3-Cyclopentanedicarboxylic acid, 1-amino-, (1R,3R)-rel- |
CAS号 | 477331-06-9 |
分子式 | C7H11NO4 |
分子量 | 173.17 |
EINECS号 | |
相关类别 | |
Mol文件 | 477331-06-9.mol |
结构式 | ![]() |
(1S,3S)-1-氨基-1,3-环戊烷二甲酸 性质
沸点 | 352.7±42.0 °C(Predicted) |
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密度 | 1.452±0.06 g/cm3(Predicted) |
储存条件 | Store at RT |
溶解度 | 1eq 中可溶解至 100 毫升氢氧化钠 |
形态 | 粉末 |
酸度系数(pKa) | 2.11±0.40(Predicted) |
NMDA 3.3 μM (IC 50 ) |
mGluR2 13 μM (EC 50 ) |
mGluR4 50 μM (EC 50 ) |
cis-ACPD is a selective group II mGluR agonist, with EC
50
s of 13, 50, >300 and >300 μM for mGluR2, mGluR4, mGluR1 and mGluR5, respectively.
cis-ACPD (1-1000 µM; 60 min) stimulates hydrolysis of
3
H-phosphoinositide.
cis-ACPD (1-1000 mg/kg; i.p.) produces dose-related convulsions in rats.