|
(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-12-oxo-1,2,3,4,5,6,7,8,9,11,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid Suppliers list
|
| Company Name: |
ChemStrong Scientific Co.,Ltd
|
| Tel: |
0755-0755-66853366 13670046396 |
| Email: |
sales@chem-strong.com |
| Products Intro: |
Product Name:12-Ketolithocholic acid
CAS:5130-29-0
Purity:95% HPLC Package:10mg;25mg;50mg;100mg
|
| Company Name: |
Zhengzhou Huiju Chemical Co., Ltd.
|
| Tel: |
0371-55900031 18137872243 |
| Email: |
2853979815@qq.com |
| Products Intro: |
Product Name:(R)-4-((3R,5R,8R,9S,10S,13R,14S,17R)-3-Hydroxy-10,13-dimethyl-12-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid
CAS:5130-29-0
Purity:98% Package:1g ；5g ；10g ；25g ；100g ；500g ；1kg ；5kg
|
| Company Name: |
Beijing YiboYuntian Technology Co., Ltd.
|
| Tel: |
13811826434 |
| Email: |
lichen13811826434@126.com |
| Products Intro: |
Product Name:(4R)-4-((3R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-12-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid
CAS:5130-29-0
Purity:98% Package:1G/;5G/;10G/;25G/;50G/
|
|
| | (4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-12-oxo-1,2,3,4,5,6,7,8,9,11,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid Basic information |
| Product Name: | (4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-12-oxo-1,2,3,4,5,6,7,8,9,11,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid | | Synonyms: | (4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-12-oxo-1,2,3,4,5,6,7,8,9,11,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid;12-Ketodeoxycholic acid;3-ALPHA-HYDROXY-12-OXO-5-BETA-CHOLANOICACID;Cholic Acid IMpurity (3-alpha-Hydroxy-12-Oxo-5-beta-Cholanoic Acid);(4R)-4-((3R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-12-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid;Cholic Acid Impurity 9;5β-CHOLANIC acid-3α-OL-12-ONE;(R)-4-((3R,5R,8R,9S,10S,13R,14S,17R)-3-Hydroxy-10,13-dimethyl-12-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid | | CAS: | 5130-29-0 | | MF: | C24H38O4 | | MW: | 390.56 | | EINECS: | | | Product Categories: | | | Mol File: | 5130-29-0.mol | ![(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-12-oxo-1,2,3,4,5,6,7,8,9,11,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid Structure](CAS/GIF/5130-29-0.gif) |
| | (4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-12-oxo-1,2,3,4,5,6,7,8,9,11,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid Chemical Properties |
| Melting point | 165-167 °C | | Boiling point | 545.9±35.0 °C(Predicted) | | density | 1.124±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml | | form | A solid | | pka | 4.74±0.10(Predicted) | | color | White to off-white |
| | (4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-12-oxo-1,2,3,4,5,6,7,8,9,11,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid Usage And Synthesis |
| Description | 12-keto Lithocholic acid is a metabolite of the secondary bile acid deoxycholic acid (DCA; Item Nos. 20756 | 18231). Fecal levels of 12-keto lithocholic acid are elevated in rats fed a diet supplemented with cholic acid or DCA compared with rats fed a control diet or a diet supplemented with cholesterol , hyodeoxycholic acid (HDCA; ), or lithocholic acid (LCA; ). 12-keto Lithocholic acid activates the human pregnane X receptor (PXR; EC50 = 31.3 μM in a cell-based transactivation assay). 12-keto Lithocholic acid levels are increased in duodenal bile from patients with type 2 diabetes. | | Definition | ChEBI: 12-ketolithocholic acid is a bile acid. |
| | (4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-12-oxo-1,2,3,4,5,6,7,8,9,11,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid Preparation Products And Raw materials |
|