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| | ANTI-HUMAN MCP-3 Basic information |
| Product Name: | ANTI-HUMAN MCP-3 | | Synonyms: | ANTI-HUMAN CCL7;ANTI-HUMAN MCP-3;ANTI-HUMAN MCP-3 MONOCLONAL ANTIBODY;ANTI-HUMAN MCP-3 POLYCLONAL ANTIBODY;ANTI-HUMAN MARC;ANTI-HUMAN MONOCYTE CHEMOTACTIC PROTEIN-3;ANTI-MACROPHAGE/MONOCYTE CHEMOTACTIC PROTEIN-3, HUMAN;ANTI-MCP-3, HUMAN | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-HUMAN MCP-3 Structure]() |
| | ANTI-HUMAN MCP-3 Chemical Properties |
| storage temp. | −20°C | | form | lyophilized powder | | biological source | rabbit |
| | ANTI-HUMAN MCP-3 Usage And Synthesis |
| Uses | Anti-CCL7 antibody produced in rabbit is suitable for western blotting at a concentration of 0.5 μg/ml. For immunohistochemistry of paraffin-embedded tissue sections, a concentration of 4-8 μg/ml is suitable. | | Biological Activity | Chemokine (C-C motif) ligand 7 (CCL7) is a small cytokine known as a chemokine, earlier called as monocyte-specific chemokine 3 (MCP3). It regulates macrophage functions. It belongs to the monocyte chemotactic protein (MCP) subfamily of the CC chemokines and is produced by astrocytes. The CCL7 gene is mapped to chromosome 17 on subbands q11.2-q12. It induces production of gelatinase B and chemotaxis of monocytes. It is often produced by tumor cell lines and regulates protease secretion by macrophages. CCL7 production may contribute to invasion and metastasis of cancer cells. It may act as a novel target metastasis of colorectal cancer (CRC) and may be of potential clinical value for the prevention of hepatic recurrences. CCL7 may have a role in vascular pathology as well. |
| | ANTI-HUMAN MCP-3 Preparation Products And Raw materials |
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