Ezetimibe-d4 -D-Glucuronide, >85%
| 中文名称 | Ezetimibe-d4 -D-Glucuronide, >85% |
|---|---|
| 中文同义词 | 依折麦布-D4Β-D-葡糖醛酸;依泽替米贝-Β-D-葡萄糖醛酸苷-D4;化合物 EZETIMIBE-D4PHENOXY-D-GLUCURONIDE |
| 英文名称 | Ezetimibe-d4 -D-Glucuronide, >85% |
| 英文同义词 | 4-[(2S,3R)-1-(4-Fluorophenyl-d4)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxo-2-azetidinyl]phenyl-D-Glucopyranosiduronic Acid;Ezetimibe-d4 -D-Glucuronide, >85%;Ezetimibe-d4 Phenoxy Glucuronide;Sch 58235-d4 Glucuronide;Sch 60663-d4;Ezetimibe D4 Phenoxy GlucuronideQ: What is Ezetimibe D4 Phenoxy Glucuronide Q: What is the CAS Number of Ezetimibe D4 Phenoxy Glucuronide Q: What is the storage condition of Ezetimibe D4 Phenoxy Glucuronide Q: What are the applications of Ezetimibe D4 Phenoxy Glucuronide;Ezetimibe-d4 β-D-Glucuronide, >85%;Ezetimibe glucuronide-D4 |
| CAS号 | 1426174-41-5 |
| 分子式 | C30H25D4F2NO9 |
| 分子量 | 589.574013512 |
| EINECS号 | |
| 相关类别 | Inhibitors;Intermediates & Fine Chemicals;Isotope Labeled Compounds;Metabolites & Impurities;Pharmaceuticals;Glucuronide;Isotope Labelled Compounds |
| Mol文件 | 1426174-41-5.mol |
| 结构式 |  |
Ezetimibe-d4 -D-Glucuronide, >85% 性质
| 熔点 | 140-150°C |
|---|---|
| 储存条件 | -20°C Freezer |
| 溶解度 | DMSO（微溶，超声处理）、甲醇（微溶）、水（微溶） |
| 形态 | 固体 |
| 颜色 | 白色至浅棕色 |
| 稳定性 | 吸湿性 |
Ezetimibe phenoxy glucuronide-D4 (Ezetimibe glucuronide-D4) 是 Ezetimibe phenoxy glucuronide 的氘代物。Ezetimibe phenoxy glucuronide 是 Ezetimibe 的活性代谢物，具有抗高脂蛋白血症效果。Ezetimibe 是有效的胆固醇吸收抑制剂。
After oral administration, Ezetimibe is absorbed in the small intestine and more than 80% of Ezetimibe metabolized to Ezetimibe Glucuronide.