Company Name: |
SIGMA-RBI
|
Tel: |
800 736 3690 (Orders) |
Email: |
|
Products Intro: |
|
|
| Anti-sir2-like 4, Anti-SIR2L4, Anti-sirtuin 4, Anti-sirtuin type 4, Anti-Sirtuin (silent mating type information regulation 2 homolog) 4 Basic information |
| Anti-sir2-like 4, Anti-SIR2L4, Anti-sirtuin 4, Anti-sirtuin type 4, Anti-Sirtuin (silent mating type information regulation 2 homolog) 4 Chemical Properties |
| Anti-sir2-like 4, Anti-SIR2L4, Anti-sirtuin 4, Anti-sirtuin type 4, Anti-Sirtuin (silent mating type information regulation 2 homolog) 4 Usage And Synthesis |
Uses | Anti-SIRT4 has been used in immunohistochemistry. | General Description | SIRT4 (sirtuin 4) belongs to sirtuin family of nicotinamide adenine dinucleotide-dependent enzymes. It is a NAD+-dependent ADP ribosyltransferase, that is located in the mitochondria. SIRT4 protein level is found to be more in ESCC (esophageal squamous cell carcinoma) tissues. | Biochem/physiol Actions | SIRT4 (sirtuin 4) may involve in the development of esophageal cancer. Growth of HeLa cells can be suppressed by the overexpression of SIRT4. It modulates glutamine metabolism and may also act as a tumor suppressor. It plays some important roles in multiple cellular processes like stress response and longevity. It may act as an important therapeutic target in colorectal cancer. |
| Anti-sir2-like 4, Anti-SIR2L4, Anti-sirtuin 4, Anti-sirtuin type 4, Anti-Sirtuin (silent mating type information regulation 2 homolog) 4 Preparation Products And Raw materials |
|