| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Monoclonal Anti-CD3
Purity:monoclonal OKT3, purified immunoglobulin, buffered aqueous s Package:100μg Remarks:SAB4700040
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| Company Name: |
Riedel-de Haen AG
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| Tel: |
800 558-9160 |
| Email: |
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| Products Intro: |
Remarks:clone UCHT-1, purified immunoglobulin, buffered aqueous solution
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| Company Name: |
SIGMA-RBI
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| Tel: |
800 736 3690 (Orders) |
| Email: |
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| Products Intro: |
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| | Monoclonal Anti-CD3 Basic information |
| Product Name: | Monoclonal Anti-CD3 | | Synonyms: | Monoclonal Anti-CD3;Monoclonal Anti-CD3 antibody produced in mouse;Monoclonal Anti-CD3-Quantum RedTM antibody produced in mouse;Monoclonal Anti-CD3-PE antibody produced in mouse;Monoclonal Anti-CD3-FITC antibody produced in mouse;Monoclonal Anti-CD3?Quantum Red? antibody produced in mouse;Anti-CD3 (activation epitope) | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![Monoclonal Anti-CD3 Structure]() |
| | Monoclonal Anti-CD3 Chemical Properties |
| | Monoclonal Anti-CD3 Usage And Synthesis |
| Uses | The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 1 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator. | | General Description | CD3e molecule, ε (CD3E) is a polypeptide encoded by the CD3E gene in humans. It resides on chromosome 11. The CD3ε cytoplasmic domain of the T cell receptor binds to the inner leaflet of the plasma membrane (PM) and is accessible during early stages of T cell activation. It is specific for T lymphocytes and is found in Purkinje cells of the cerebellum as well as in gastric parietal cells of humans and other species. Cytoplasmic cyCD3 expression can only be seen during the early phase of NK-cell differentiation. | | Biochem/physiol Actions | T-cell receptor-CD3 complex including CD3ε, CD3γ and CD3δ, plays a vital role in inducing early metabolic events that lead to T cell activation. Mutation in the CD3ε has been observed in T-B+ NK+ severe combined immunodeficiency (SCID) patients. |
| | Monoclonal Anti-CD3 Preparation Products And Raw materials |
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