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| | 1α,4α-Epoxy-16β-hydroxy-3-aza-A-homo-5β-pregnan-21-oic acid γ-lactone Basic information |
| Product Name: | 1α,4α-Epoxy-16β-hydroxy-3-aza-A-homo-5β-pregnan-21-oic acid γ-lactone | | Synonyms: | 1α,4α-Epoxy-16β-hydroxy-3-aza-A-homo-5β-pregnan-21-oic acid γ-lactone;Samandaridine;2,5-Epoxyfuro[3'',2'':3',4']cyclopenta[1',2':5,6]naphth[1,2-d]azepin-9(1H)-one, octadecahydro-5a,7a-dimethyl-, (2S,5R,5aS,5bS,7aS,7bR,10aS,11aS,11bS,13aR)- | | CAS: | 6384-73-2 | | MF: | C21H31NO3 | | MW: | 345.48 | | EINECS: | | | Product Categories: | | | Mol File: | 6384-73-2.mol |  |
| | 1α,4α-Epoxy-16β-hydroxy-3-aza-A-homo-5β-pregnan-21-oic acid γ-lactone Chemical Properties |
| Melting point | 287-8°C | | Boiling point | 498.9±45.0 °C(Predicted) | | density | 1.153±0.06 g/cm3(Predicted) | | pka | 8.69±0.60(Predicted) |
| | 1α,4α-Epoxy-16β-hydroxy-3-aza-A-homo-5β-pregnan-21-oic acid γ-lactone Usage And Synthesis |
| Description | A hex acyclic alkaloid present in the skin secretions of various species of Salamandra (salamanders), the base yields a crystalline hydrochloride, m.p. 343°C;
[α]24578 + 14.1° and a hydrobromide which crystallizes from MeOH with solvent
of crystallization, m.p. 346°C. The structure has been determined from the
infrared, NMR and mass spectra. | | References | Schopf, Koch., Annalen, 552,41 (1942)
Habermehl., Chem. Ber., 96, 143,840 (1963) |
| | 1α,4α-Epoxy-16β-hydroxy-3-aza-A-homo-5β-pregnan-21-oic acid γ-lactone Preparation Products And Raw materials |
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