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| (2R)-6-Amino-1,2,3,4-tetrahydro-2-(1-hydroxy-1-methylethyl)-9-methyl-7H-benzocyclohepten-7-one Basic information |
| (2R)-6-Amino-1,2,3,4-tetrahydro-2-(1-hydroxy-1-methylethyl)-9-methyl-7H-benzocyclohepten-7-one Chemical Properties |
| (2R)-6-Amino-1,2,3,4-tetrahydro-2-(1-hydroxy-1-methylethyl)-9-methyl-7H-benzocyclohepten-7-one Usage And Synthesis |
Occurrence | The root bark of Dulacia guianensis yields manicolines A and B which have been separated
by chromatographic methods. This component forms pale yellow crystals from AcOEt and
is dextrorotatory with a specific rotation of [α]D +69° (c 0.9, CHC13 + 10% EtOH). Manicoline A is not cytotoxic for chick embryo fibroblasts up to doses of 5 Il. g/mL
and does not inhibit cell transformation induced by Rous sarcoma virus. |
| (2R)-6-Amino-1,2,3,4-tetrahydro-2-(1-hydroxy-1-methylethyl)-9-methyl-7H-benzocyclohepten-7-one Preparation Products And Raw materials |
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