N2-(6-Methyloctanoyl-L-A2bu-L-Thr-L-A2bu-)cyclo(L-A2bu*-L-A2bu-D-Leu-L-Leu-L-A2bu-L-A2bu-L-Thr-)
| 中文名称 | N2-(6-Methyloctanoyl-L-A2bu-L-Thr-L-A2bu-)cyclo(L-A2bu*-L-A2bu-D-Leu-L-Leu-L-A2bu-L-A2bu-L-Thr-) |
|---|---|
| 中文同义词 | 多粘菌素 E1;606423 |
| 英文名称 | N2-(6-Methyloctanoyl-L-A2bu-L-Thr-L-A2bu-)cyclo(L-A2bu*-L-A2bu-D-Leu-L-Leu-L-A2bu-L-A2bu-L-Thr-) |
| 英文同义词 | Colistin A;N2-(6-Methyl-1-oxooctyl-L-A2bu-L-Thr-L-A2bu-)cyclo(L-A2bu*-L-A2bu-D-Leu-L-Leu-L-A2bu-L-A2bu-L-Thr-);N2-(6-Methyloctanoyl-L-A2bu-L-Thr-L-A2bu-)cyclo(L-A2bu*-L-A2bu-D-Leu-L-Leu-L-A2bu-L-A2bu-L-Thr-);Polymyxin E1;XQKABMNFUQVRFN-SADGAIANSA-N;Colistin A-d5 Discontinued;Colistin IV;Polymixin E1 |
| CAS号 | 7722-44-3 |
| 分子式 | C53H100N16O13 |
| 分子量 | 1169.46 |
| EINECS号 | |
| 相关类别 | Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals |
| Mol文件 | 7722-44-3.mol |
| 结构式 |  |
N2-(6-Methyloctanoyl-L-A2bu-L-Thr-L-A2bu-)cyclo(L-A2bu*-L-A2bu-D-Leu-L-Leu-L-A2bu-L-A2bu-L-Thr-) 性质
| 比旋光度 | 225461 -93.3° (2% acetic acid) |
|---|---|
| 沸点 | 1536.8±65.0 °C(Predicted) |
| 密度 | 1.25±0.1 g/cm3(Predicted) |
| 溶解度 | 甲醇（微溶）、水（微溶） |
| 形态 | 固体 |
| 酸度系数(pKa) | 13.08±0.70(Predicted) |
| 颜色 | 白色至浅棕色 |
N2-(6-Methyloctanoyl-L-A2bu-L-Thr-L-A2bu-)cyclo(L-A2bu*-L-A2bu-D-Leu-L-Leu-L-A2bu-L-A2bu-L-Thr-) 用途与合成方法
Colistin A 是 Colistin 的一种主要成分。Colistin 是一种多粘菌素抗生素 (antibiotic)。Colistin 可用来对抗由革兰氏阴性菌引起的感染。