Company Name: |
Chengdu Greenpure Biopharma CO.,Ltd
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Tel: |
028-88203606; 18283602253 |
Email: |
jancyzheng@gcgreenpure.com |
Products Intro: |
Product Name:Stepharine CAS:2810-21-1 Purity:98% Package:100mg/
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| (8'aR)-2',3',8',8'a-Tetrahydro-5',6'-dimethoxyspiro[2,5-cyclohexadiene-1,7'(1'H)-cyclopenta[ij]isoquinoline]-4-one Basic information |
Product Name: | (8'aR)-2',3',8',8'a-Tetrahydro-5',6'-dimethoxyspiro[2,5-cyclohexadiene-1,7'(1'H)-cyclopenta[ij]isoquinoline]-4-one | Synonyms: | (+)-Stepharine;(8'aR)-2',3',8',8'a-Tetrahydro-5',6'-dimethoxyspiro[2,5-cyclohexadiene-1,7'(1'H)-cyclopent[ij]isoquinolin]-4-one;(8'aR)-2',3',8',8'a-Tetrahydro-5',6'-dimethoxyspiro[2,5-cyclohexadiene-1,7'(1'H)-cyclopenta[ij]isoquinoline]-4-one;Stepharine;Spiro[2,5-cyclohexadiene-1,7'(1'H)-cyclopent[ij]isoquinolin]-4-one, 2',3',8',8'a-tetrahydro-5',6'-dimethoxy-, (8'aR)-;(+)-Stepharine | CAS: | 2810-21-1 | MF: | C18H19NO3 | MW: | 297.34836 | EINECS: | | Product Categories: | | Mol File: | 2810-21-1.mol | |
| (8'aR)-2',3',8',8'a-Tetrahydro-5',6'-dimethoxyspiro[2,5-cyclohexadiene-1,7'(1'H)-cyclopenta[ij]isoquinoline]-4-one Chemical Properties |
Melting point | 179-181 °C | Boiling point | 487.1±45.0 °C(Predicted) | density | 1.27±0.1 g/cm3(Predicted) | storage temp. | 4°C, protect from light | form | Solid | pka | 8.08±0.20(Predicted) | color | Pale purple to purple |
| (8'aR)-2',3',8',8'a-Tetrahydro-5',6'-dimethoxyspiro[2,5-cyclohexadiene-1,7'(1'H)-cyclopenta[ij]isoquinoline]-4-one Usage And Synthesis |
Description | A spiroisoquinoline alkaloid from Stephania glabra, the base has [α]26D + 143°
(c 1.88, CHCI3). It contains two methoxyl groups and an imino group and yields
a crystalline N-acetyl derivative, m.p. 234-5°C; [α]24D- 80° (c 1.57, CHCI3).
The N-methyl compound has been shown to be identical with Pronuciferine
(q.v.). | References | Cava et al., Chern. Ind., 282 (1964)
Tomita et al., Tetrahedron Lett., 2825 (1965)
Baldwin et al., J. Chern. Soc., C, 154 (1967)
Circular dichroism:
Snatzke, Wollenberg., J. Chern. Soc., C, 1681 (1966) |
| (8'aR)-2',3',8',8'a-Tetrahydro-5',6'-dimethoxyspiro[2,5-cyclohexadiene-1,7'(1'H)-cyclopenta[ij]isoquinoline]-4-one Preparation Products And Raw materials |
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