| Company Name: |
Riedel-de Haen AG
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| Tel: |
800 558-9160 |
| Email: |
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| Products Intro: |
Remarks:affinity isolated antibody, aqueous glycerol suspension, 10 nm (colloidal gold)
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| Company Name: |
SIGMA-RBI
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| Tel: |
800 736 3690 (Orders) |
| Email: |
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| Products Intro: |
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| | ANTI-IGG WHOLE MOLECULE GOLD LABELED CONJUGATE Basic information |
| | ANTI-IGG WHOLE MOLECULE GOLD LABELED CONJUGATE Chemical Properties |
| storage temp. | 2-8°C | | form | aqueous glycerol suspension |
| | ANTI-IGG WHOLE MOLECULE GOLD LABELED CONJUGATE Usage And Synthesis |
| Uses | Anti-rabbit IgG (whole molecule)-gold antibody (diluted 1: 15) can be used in immunoelectron microscopy. It can also be used in western blotting. | | General Description | Rabbit IgG is a plasma B cell derived antibody isotype defined by its heavy chain. IgG is the most abundant antibody isotype found in rabbit serum. IgG crosses the placental barrier, is a complement activator and binds to the Fc-receptors on phagocytic cells. The level of IgG may vary with the status of disease or infection.
Immunogold labeling is a technique whereing antibodies, especially secondary antibodies, are labeled with colloidal gold. These gold conjugated antibodies generate electron dense particles that are visable using electron microscopy. | | Biochem/physiol Actions | Digestion of IgG by papain results in generation of fragment antigen binding (Fab). Pepsin digestion of IgG results in fragment crystallizable (Fc). Fc regions of IgG antibody have enormous therapeutic potential and are exploited for the development of therapeutic antibodies. IgG1 class is the most abundant and its deficiency results in hypogammaglobulinemia. IgG2 deficiency increases susceptibility to bacterial infections. IgG3 mediates effector functions and IgG4 is associated with asymptomatic infection. |
| | ANTI-IGG WHOLE MOLECULE GOLD LABELED CONJUGATE Preparation Products And Raw materials |
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