219757-90-1
中文名称 | 219757-90-1 |
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中文同义词 | 化合物 T13021 |
英文名称 | SULAMSEROD |
英文同义词 | SULAMSEROD;RS-100302;Methanesulfonamide, N-[2-[4-[3-(8-amino-7-chloro-2,3-dihydro-1,4-benzodioxin-5-yl)-3-oxopropyl]-1-piperidinyl]ethyl]- |
CAS号 | 219757-90-1 |
分子式 | C19H28ClN3O5S |
分子量 | 445.96 |
EINECS号 | |
相关类别 | |
Mol文件 | 219757-90-1.mol |
结构式 | ![]() |
219757-90-1 性质
沸点 | 647.8±65.0 °C(Predicted) |
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密度 | 1.319±0.06 g/cm3(Predicted) |
储存条件 | Store at -20°C |
溶解度 | 溶于二甲基亚砜 |
酸度系数(pKa) | 11.22±0.40(Predicted) |
5-HT 4 Receptor
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Sulamserod (30 mg/kg) prolongs mean ERP (11568 versus 14667 ms, P,0.01) and wavelength (8.360.9 versus 9.960.8 cm, P,0.01), reduces dispersion of ERP (1565 versus 861 ms, P,0.01), and minimally slows conduction velocity (7264 versus 6765 cm/s, P,0.01) in pigs. Sulamserod produces no ventricular electrophysiological effects. Sulamserod terminates atrial flutter in 6 of 8 animals and atrial fibrillation in 8 of 9 animals and prevents reinduction of sustained tachycardia in all animals.