AM2201 N-(4-hydroxypentyl) metabolite

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AM2201 N-(4-hydroxypentyl) metabolite Basic information
Product Name:AM2201 N-(4-hydroxypentyl) metabolite
Synonyms:AM2201 N-(4-hydroxypentyl) metabolite;[1-(5-fluoro-4-hydroxypentyl)indol-3-yl]-naphthalen-1-ylmethanone;(1-(5-fluoro-4-hydroxypentyl)-1H-indol-3-yl)(naphthalen-1-yl)methanone;AM-2201 4-hydroxypentyl metabolite;AM-2201 4-hydroxypenty metabolite;Methanone, [1-(5-fluoro-4-hydroxypentyl)-1H-indol-3-yl]-1-naphthalenyl-
CAS:1427521-34-3
MF:C24H22FNO2
MW:375.44
EINECS:
Product Categories:
Mol File:1427521-34-3.mol
AM2201 N-(4-hydroxypentyl) metabolite Structure
AM2201 N-(4-hydroxypentyl) metabolite Chemical Properties
Boiling point 603.6±50.0 °C(Predicted)
density 1.19±0.1 g/cm3(Predicted)
solubility Dichloromethane: 20 mg/ml; DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 5 mg/ml
pka13.87±0.20(Predicted)
Safety Information
MSDS Information
AM2201 N-(4-hydroxypentyl) metabolite Usage And Synthesis
DescriptionAM2201 is a potent synthetic cannabinoid (CB) with Ki values of 1.0 and 2.6 nM for the CB1 and CB2 receptors, respectively.1 AM2201 N-(4-hydroxypentyl) metabolite is an expected urinary metabolite of AM2201, based on the known metabolism of similar compounds.2 Its biological actions are unknown.
Uses4-Hydroxypentyl AM-2201 is a metabolite of AM-2201 (A575830), is a drug which acts as a potent but unselective agonist for the cannabinoid receptor CB1 or CB2.
References1. Makriyannis, A., and Deng, H. Cannabimimetic indole derivatives US7241799B2,(2001).
2. Wintermeyer, A., M?ller, I., Thevis, M., et al. In vitro phase I metabolism of the synthetic cannabimimetic JWH-018 Anal. Bioanal. Chem. 398(5),2141-2153(2010).
AM2201 N-(4-hydroxypentyl) metabolite Preparation Products And Raw materials
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