4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline

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Products Intro: Product Name:4-((4-Ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline
CAS:630125-91-6
Purity:0.98 Package:1KG;10KG;100KG;1000KG
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Products Intro: Product Name:4-((4-Ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline
CAS:630125-91-6
Purity:98% Min. Remarks:MC431954
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Products Intro: Product Name:4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline
CAS:630125-91-6
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Products Intro: Product Name:4-((4-Ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline
CAS:630125-91-6
Purity:97% Package:$904.9/5g;Bulk package Remarks:97%
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Products Intro: Product Name:4-((4-Ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline
CAS:630125-91-6
Purity:0.97 Package:5KG;1KG;100g;25g;10g;5g
4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline Basic information
Product Name:4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline
Synonyms:4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline;4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)aniline;Benzenamine, 4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)-
CAS:630125-91-6
MF:C14H20F3N3
MW:287.32
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Mol File:630125-91-6.mol
4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline Structure
4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline Chemical Properties
Boiling point 344.9±42.0 °C(Predicted)
density 1.195±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility soluble in Dichloromethane;
form Solid
pka7.76±0.10(Predicted)
color Yellow
Safety Information
MSDS Information
4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline Usage And Synthesis
Uses4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)-benzenamine is one of the key reactants with N-[1-(4-Aminophenyl)-1H-pyrrolo[3,2-c]pyridin-4-yl]benzamide used in the synthesis of a pyrrolo[3,2-c]pyridine derivative [N-[1-[4-[[[[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenyl]-1H-pyrrolo[3,2-c]pyridin-4-yl]benzamide (I)], an anticancer diarylurea derivative with multiple-kinase inhibitory effect; Also, it is an intermediate used in the synthesis of N-[4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-N''-[4-[[6-(methylamino)-4-pyrimidinyl]oxy]phenyl]urea (E926495), which is an inhibitor of RET, FLT3, KDR, c-Abl and c-Kit. Also, it prevent the growth of human thyroid cancer cells.
4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline Preparation Products And Raw materials
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