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ATB 346

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Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:ATB 346
CAS:1226895-20-0
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
Company Name: BOC Sciences
Tel: +1-631-485-4226
Email: inquiry@bocsci.com
Products Intro: Product Name:ATB 346
CAS:1226895-20-0
Package:50mg Remarks:BOC Sciences also provides custom synthesis services for ATB 346.
Company Name: career henan chemical co
Tel: +86-0371-86658258 +8613203830695
Email: factory@coreychem.com
Products Intro: Product Name:ATB 346
CAS:1226895-20-0
Purity:99% Package:1KG;1USD
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:Otenaproxesul
CAS:1226895-20-0
Purity:99.23% Package:5mg;33USD|10mg;53USD|25mg;107USD Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel: 86-571-88216897,88216896 13588875226
Email: sales@hzclap.com
Products Intro: Product Name:ATB 346
CAS:1226895-20-0
Purity:34299% Package:10kg 25kg 200 kilograms per barrel Remarks:good

ATB 346 manufacturers

  • Otenaproxesul
  • Otenaproxesul pictures
  • $34.00 / 2mg
  • 2024-11-19
  • CAS:1226895-20-0
  • Min. Order:
  • Purity: 99.23%
  • Supply Ability: 10g
  • ATB 346
  • ATB 346 pictures
  • $1.00 / 1KG
  • 2020-01-03
  • CAS:1226895-20-0
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 200kg
ATB 346 Basic information
Product Name:ATB 346
Synonyms:ATB 346;4-CARBAMOTHIOYLPHENYL 2-(6-METHOXYNAPHTHALEN-2-YL)PROPANOATE;ABT-346;6-Methoxy-alpha-methyl-2-naphthaleneacetic acid 4-(aminothioxomethyl)phenyl ester;6-Methoxy-alpha-methyl-2-naphthaleneacetic acid 4-(aminothioxomethyl)phenyl ester ATB 346;ATB 346 6-Methoxy-alpha-methyl-2-naphthaleneacetic acid 4-(aminothioxomethyl)phenyl ester;ATB-346, >=98%;ATB 346,1226895-20-0
CAS:1226895-20-0
MF:C21H19NO3S
MW:365.45
EINECS:
Product Categories:Inhibitors
Mol File:1226895-20-0.mol
ATB 346 Structure
ATB 346 Chemical Properties
Boiling point 561.4±60.0 °C(Predicted)
density 1.261±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility insoluble in EtOH; insoluble in H2O; ≥18.27 mg/mL in DMSO
form solid
pka12.37±0.29(Predicted)
color Light yellow to yellow
Safety Information
MSDS Information
ATB 346 Usage And Synthesis
DescriptionATB-346 is a non-steroidal anti-inflammatory drug (NSAID) that releases hydrogen sulfide (H2S) and a derivative of naproxen . It inhibits the proliferation of, and induces apoptosis in, A375 melanoma cells when used at a concentration of 100 μM. ATB-346 decreases prostaglandin E2 (PGE2) production in inflammatory exudates, reduces paw edema, and increases plasma levels of sulfide in a mouse model of zymosan-induced arthritis. It reduces the size of acetic acid-induced gastric ulcers in mice when administered at a dose of 60 μmol/kg. ATB-346 (30 μmol/kg) improves motor function in a mouse model of spinal cord injury.
references[1] wallace j l, caliendo g, santagada v, et al. markedly reduced toxicity of a hydrogen sulphide-releasing derivative of naproxen (atb-346). british journal of pharmacology, 2010, 159(6): 1236-1246.
ATB 346 Preparation Products And Raw materials
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