Company Name: |
Jiangsu Vcare PharmaTech Co., Ltd.
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Tel: |
13327700685 |
Email: |
sales@vcarepharmatech.com |
Products Intro: |
Product Name:2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aMinocarbonyl)-, 1,1-diMethylethyl ester, (1R,3S,5R)- CAS:1445592-86-8
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Company Name: |
ChemStrong Scientific Co.,Ltd
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Tel: |
0755-0755-66853366 13670046396 |
Email: |
sales@chem-strong.com |
Products Intro: |
Product Name:Saxagliptin Impurity 27 CAS:1445592-86-8 Purity:95% HPLC Package:10mg;25mg;50mg;100mg
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| 2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aMinocarbonyl)-, 1,1-diMethylethyl ester, (1R,3S,5R)- Basic information |
Product Name: | 2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aMinocarbonyl)-, 1,1-diMethylethyl ester, (1R,3S,5R)- | Synonyms: | 2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aMinocarbonyl)-, 1,1-diMethylethyl ester, (1R,3S,5R)- | CAS: | 1445592-86-8 | MF: | C11H18N2O3 | MW: | 226.27 | EINECS: | | Product Categories: | | Mol File: | 1445592-86-8.mol | |
| 2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aMinocarbonyl)-, 1,1-diMethylethyl ester, (1R,3S,5R)- Chemical Properties |
Boiling point | 388.9±21.0 °C(Predicted) | density | 1.228±0.06 g/cm3(Predicted) | pka | 16.00±0.20(Predicted) |
| 2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aMinocarbonyl)-, 1,1-diMethylethyl ester, (1R,3S,5R)- Usage And Synthesis |
Uses | tert-Butyl (1R,3S,5R)-3-Carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate is an intermediate in the synthesis of ((2S,2R’,trans)-Saxagliptin (S143495), which is an impurity of Saxagliptin (S143500). Saxagliptin is a potent and selective reversible inhibitor of dipeptidyl peptidase-4 (DPP-IV) developed for the treatment of type 2 diabetes. |
| 2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aMinocarbonyl)-, 1,1-diMethylethyl ester, (1R,3S,5R)- Preparation Products And Raw materials |
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