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| Pyrido[2,3-d]pyriMidin-7(8H)-one, 8-cyclopentyl-5-Methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]aMino]- Basic information |
Product Name: | Pyrido[2,3-d]pyriMidin-7(8H)-one, 8-cyclopentyl-5-Methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]aMino]- | Synonyms: | 8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one;8-Cyclopentyl-5-methyl-2-[[(5-piperazin-1-ylpyridin-2-yl)]amino]-8H-pyrido[2,3-d]pyrimidin-7-one;6-Desacetyl Palbociclib;Palbociclib impurity 12/8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one;Palbociclib-1;Palbociclib-010;8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)a...;8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]- Pyrido[2,3-d]pyrimidin-7(8H)-one | CAS: | 571190-22-2 | MF: | C22H27N7O | MW: | 405.5 | EINECS: | | Product Categories: | | Mol File: | 571190-22-2.mol | |
| Pyrido[2,3-d]pyriMidin-7(8H)-one, 8-cyclopentyl-5-Methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]aMino]- Chemical Properties |
Melting point | >200oC (dec.) | Boiling point | 651.3±65.0 °C(Predicted) | density | 1.301±0.06 g/cm3(Predicted) | storage temp. | -20°C, Inert atmosphere | solubility | Acetonitrile (Slightly), Chloroform (Slightly) | pka | 8.66±0.10(Predicted) | form | Solid | color | Light Yellow |
| Pyrido[2,3-d]pyriMidin-7(8H)-one, 8-cyclopentyl-5-Methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]aMino]- Usage And Synthesis |
Uses | 6-Desacetyl Palbociclib is an impurity of Palbociclib (P139900),(also known as compound number PD-0332991) is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. |
| Pyrido[2,3-d]pyriMidin-7(8H)-one, 8-cyclopentyl-5-Methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]aMino]- Preparation Products And Raw materials |
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