| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:N-C16-deoxysphinganine
CAS:378755-69-2
Purity:N-palmitoyl-1-deoxysphinganine (m18:0/16:0), powder Package:5MG Remarks:860462P-5MG
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| Company Name: |
Codow Chemical Co.,Ltd.
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| Tel: |
18620099427 |
| Email: |
amy@howeipharm.com |
| Products Intro: |
Product Name:N-palmitoyl-1-deoxysphinganine (m18:0/16:0)
CAS:378755-69-2
Purity:>99% Package:1MG;2.5MG;5MG;10MG
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| Company Name: |
Chengdu Dianchun Technology Co., Ltd
|
| Tel: |
400-1166-196 18502815961 |
| Email: |
cdhxsj@163.com |
| Products Intro: |
Product Name:N-palmitoyl-1-deoxysphinganine (m18:0/16:0)
CAS:378755-69-2
Purity:99% HPLC Package:10g;50g;100g;500g;1kg;5kg;25kg
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| | N-palMitoyl-1-deoxysphinganine (M18:0/16:0) Basic information |
| | N-palMitoyl-1-deoxysphinganine (M18:0/16:0) Chemical Properties |
| Boiling point | 635.5±38.0 °C(Predicted) | | density | 0.882±0.06 g/cm3(Predicted) | | storage temp. | -20°C | | pka | 14.54±0.20(Predicted) |
| | N-palMitoyl-1-deoxysphinganine (M18:0/16:0) Usage And Synthesis |
| General Description | N-C16-deoxysphinganine Commonly referred to as 1-deoxydihydroceramide (1-deoxyDHCer), is the N-acylated form of 1-deoxysphinganine, a potent inhibitor of sphingolipid metabolism. The N-acyl group can be 16, 20 and 24 carbon chain. N-acylsphinganines (dihydroceramides) are synthesized by the acylation of sphingoid bases in the presence of ceramide synthases (CerS). | | Biochem/physiol Actions | N-acylsphinganines (dihydroceramides) levels are lower during ceramide synthase inhibition. They are intermediates of ceramide and dihydrosphingolipids synthesis. Treatment of MCF7 cancer cells with fenretinide alters sphingolipid metabolism. |
| | N-palMitoyl-1-deoxysphinganine (M18:0/16:0) Preparation Products And Raw materials |
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