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Product Name: | BGT226 | Synonyms: | BGT-226 free base;8-(6-Methoxypyridin-3-yl)-3-methyl-1-[4-(piperazin-1-yl)-3-trifluoromethylphenyl]-1,3-dihydroimidazo[4,5-c]quinolin-2-one;2H-Imidazo[4,5-c]quinolin-2-one, 1,3-dihydro-8-(6-methoxy-3-pyridinyl)-3-methyl-1-[4-(1-piperazinyl)-3-(trifluoromethyl)phenyl]-;inhibit,Mammalian target of Rapamycin,BGT226,PI3K,BGT 226,Autophagy,BGT-226,Inhibitor,mTOR,Phosphoinositide 3-kinase | CAS: | 915020-55-2 | MF: | C28H25F3N6O2 | MW: | 534.53 | EINECS: | | Product Categories: | | Mol File: | 915020-55-2.mol | ![BGT226 Structure](CAS/20180713/GIF/915020-55-2.gif) |
| BGT226 Chemical Properties |
storage temp. | Store at -20°C | solubility | Soluble in DMSO | form | Solid | color | White to off-white |
| BGT226 Usage And Synthesis |
Uses | 8-(6-Methoxypyridin-3-yl)-3-methyl-1-(4-piperazin-1-yl)-3-(trifluoromethyl)phenyl-1H-imidazol[4,5-c]quinolin-2(3H)-one is an intermediate used in the screening of anti-prostate cancer drug targeting PI3K-AKT-mTOR pathway. | Definition | ChEBI: BGT226 free base is an imidazoquinoline that is 3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]quinoline substituted at position 1 by a 3-trifluoromethyl-4-(piperazin-1-yl)phenyl group and at position 8 by a 6-methoxypyridin-3-yl group. A dual PI3K/mTOR inhibitor. It has a role as an antineoplastic agent, a mTOR inhibitor and an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor. It is an imidazoquinoline, a N-arylpiperazine, a member of pyridines, an organofluorine compound and an aromatic ether. It is a conjugate base of a BGT226(1+). |
| BGT226 Preparation Products And Raw materials |
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