IX 207-887
中文名称 | IX 207-887 |
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中文同义词 | 化合物 T11697 |
英文名称 | (Z)-10-METHOXY-4H-BENZO[4,5]CYCLOHEPTA[1,2-B]THIOPHENE-4-YLIDENE ACETIC ACID |
英文同义词 | IX 207-887;[10-Methoxy-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene]acetic acid;(Z)-10-METHOXY-4H-BENZO[4,5]CYCLOHEPTA[1,2-B]THIOPHENE-4-YLIDENE ACETIC ACID;Acetic acid, 2-(10-methoxy-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-;IX 207 887,IX 207887 |
CAS号 | 98320-39-9 |
分子式 | C16H12O3S |
分子量 | 284.33 |
EINECS号 | |
相关类别 | |
Mol文件 | 98320-39-9.mol |
结构式 | ![]() |
IX 207-887 性质
沸点 | 475.0±45.0 °C(Predicted) |
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密度 | 1.37±0.1 g/cm3(Predicted) |
储存条件 | Store at -20°C |
溶解度 | 溶于二甲基亚砜 |
酸度系数(pKa) | 3.81±0.41(Predicted) |
形态 | 固体 |
颜色 | 浅黄至黄色 |
IL-1
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IX 207-887 is a novel antiarthritic agent which inhibits the release of interleukin-1 (IL-1) from human monocytes and mouse peritoneal macrophages. In all test systems IX 207-887 significantly reduces both biologically active and immunoreactive IL-1 in culture media, whereas the levels of IL-1 in homogenates or lysates are either unaffected or only marginally reduced. IX 207-887 neither affects the adherence of human monocytes nor markedly inhibits IL-1 or IL-2-induced thymocyte proliferation. In the chondrocyte test no IL-1 antagonistic activity of IX 207-887 can be observed.