| Company Name: |
Merck KGaA
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| Tel: |
21-20338288 |
| Email: |
ordercn@merckgroup.com |
| Products Intro: |
Product Name:Anti-DNAJB11 antibody produced in rabbit
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| Company Name: |
Riedel-de Haen AG
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| Tel: |
800 558-9160 |
| Email: |
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| Products Intro: |
Purity:affinity isolated antibody, lyophilized powder Remarks:~1 mg/mL, affinity isolated antibody, buffered aqueous solution
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| | Anti-hDj9 antibody produced in rabbit Basic information |
| Product Name: | Anti-hDj9 antibody produced in rabbit | | Synonyms: | Anti-DnaJ homolog subfamily B member 11 precursor antibody produced in rabbit;Anti-DNAJB11 antibody produced in rabbit;Anti-ER-associated dnaJ protein 3 antibody produced in rabbit;Anti-ER-associated Hsp40 co-chaperone antibody produced in rabbit;Anti-ErJ3 antibody produced in rabbit;Anti-hDj9 antibody produced in rabbit;Anti-PWP1-interacting protein 4 antibody produced in rabbit;DnaJ homolog subfamily B member 11 | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![Anti-hDj9 antibody produced in rabbit Structure]() |
| | Anti-hDj9 antibody produced in rabbit Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous glycerol solution | | biological source | rabbit |
| | Anti-hDj9 antibody produced in rabbit Usage And Synthesis |
| Uses | Anti-DNAJB11 antibody is suitable for immunoprecipitation. Anti-DNAJB11 antibody produced in rabbit, a Prestige Antibody, is developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org). Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. These images can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. The antibodies are also tested using immunofluorescence and western blotting. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit . | | General Description | DNAJB11 (DnaJ (Hsp40) homolog, subfamily B, member 11) belongs to family of endoplasmic reticulum (ER) Hsp40/DnaJ family. It is a part of ERAD (Endoplasmic-reticulum-associated protein degradation), and is a heat shock protein 40 (HSP40) chaperone. It contains the J domain, which is a highly conserved region made of 75 amino acids. It also shares certain domains with other HSP40 chaperones. These domains include a C-terminal domain, a glycine/phenylalanine-rich putative linker region and a cystine-rich domain. It is a soluble glycoprotein, oriented towards the luminal region of endoplasmic reticulum (ER). DNAJB11 is expressed ubiquitously, and has the highest expression in secretory tissues. | | Biochem/physiol Actions | DNAJB11 (DnaJ (Hsp40) homolog, subfamily B, member 11) is a part of unassembled immunoglobulin (Ig) heavy chain:BiP (binding immunoglobulin protein) complex, where it acts as a co-factor for BiP, and helps in folding and assembly of proteins. It plays a major role in mammalian cell resistance to vero toxin. It is also involved in ER (endoplasmic reticulum) stress tolerance. It is secreted in the extracellular space, where it binds to mis-folded proteins and prevents their aggregation. It also reduces the toxicity of disease-related prion protein. DNAJB11 is involved in the intoxication pathway of cholera toxin. |
| | Anti-hDj9 antibody produced in rabbit Preparation Products And Raw materials |
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