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| Kushenol K Basic information |
Product Name: | Kushenol K | Synonyms: | Kushenol K;(2R,3S)-2-(2,4-Dihydroxyphenyl)-2,3-dihydro-3,7-dihydroxy-8-[(2R)-5-hydroxy-5-methyl-2-(1-methylethenyl)hexyl]-5-methoxy-4H-1-benzopyran-4-one;product/154906;4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-2,3-dihydro-3,7-dihydroxy-8-[(2R)-5-hydroxy-5-methyl-2-(1-methylethenyl)hexyl]-5-methoxy-, (2R,3S)- | CAS: | 101236-49-1 | MF: | C26H32O8 | MW: | 472.53 | EINECS: | | Product Categories: | | Mol File: | 101236-49-1.mol | ![Kushenol K Structure](CAS/20180906/GIF/101236-49-1.gif) |
| Kushenol K Chemical Properties |
solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | form | Powder |
| Kushenol K Usage And Synthesis |
Biological Activity | Kushenol K, a flavonoid antioxidant from Sophora flavescens. It can inhibit the activity of SGLT1 and SGLT2 and used as an inhibitor of CYP3A4 with a Ki value of 1.35 μM. | in vivo | When Midazolam is used as the substrate of CYP3A4, Kushenol K exhibits the strong inhibition with an IC 50 values of 1.62 μM. At a concentration of 50 μM, the The inhibition rate of Kushenol K on SGLT1 is 29.7%, and the inhibition rate on SGLT2 is 43.7%. | target | PDE |
| Kushenol K Preparation Products And Raw materials |
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