| Company Name: |
ShangHai Caerulum Pharma Discovery Co., Ltd.
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| Tel: |
18149758185 |
| Email: |
sales-cpd@caerulumpharma.com |
| Products Intro: |
Product Name:N-(6-(4-(5-Amino-1,3,4-Thiadiazol-2-Yl)Butyl)Pyridazin-3-Yl)-2-(3-(Trifluoromethoxy)Phenyl)Acetamide
CAS:1439399-45-7
Purity:98% Package:25g;5g;1g
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| Company Name: |
Shanghai CP Pharmaceutical Technology Co., Ltd.
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| Tel: |
18221530285 |
| Email: |
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| Products Intro: |
Product Name:N-(6-(4-(5-Amino-1,3,4-Thiadiazol-2-Yl)Butyl)Pyridazin-3-Yl)-2-(3-(Trifluoromethoxy)Phenyl)Acetamide
CAS:1439399-45-7
Purity:95%+ Package:10g;25g;50g;100g,500g,1kg Remarks:L
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| Company Name: |
Wuxi AppTec
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| Tel: |
022-59987777 13552403979 |
| Email: |
jia_guoqiang@wuxiapptec.com |
| Products Intro: |
Product Name:N-(6-(4-(5-amino-1,3,4-thiadiazol-2-yl)butyl)pyridazin-3-yl)-2-(3-(trifluoromethoxy)phenyl)acetamide
CAS:1439399-45-7
Purity:95%+ Package:1G,5G,10G,25G,50G,100G,250G Remarks:in stock
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| Company Name: |
Aikon International Limited
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| Tel: |
025-66113011 18112977050 |
| Email: |
sales01@aikonchem.com |
| Products Intro: |
Product Name:N-(6-(4-(5-Amino-1,3,4-Thiadiazol-2-Yl)Butyl)Pyridazin-3-Yl)-2-(3-(Trifluoromethoxy)Phenyl)Acetamide
CAS:1439399-45-7
Purity:95+% Package:1g;5g;10g
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| | N-(6-(4-(5-Amino-1,3,4-Thiadiazol-2-Yl)Butyl)Pyridazin-3-Yl)-2-(3-(Trifluoromethoxy)Phenyl)Acetamide Basic information |
| Product Name: | N-(6-(4-(5-Amino-1,3,4-Thiadiazol-2-Yl)Butyl)Pyridazin-3-Yl)-2-(3-(Trifluoromethoxy)Phenyl)Acetamide | | Synonyms: | N-(6-(4-(5-Amino-1,3,4-Thiadiazol-2-Yl)Butyl)Pyridazin-3-Yl)-2-(3-(Trifluoromethoxy)Phenyl)Acetamide;Glutaminase-IN-3;N-[6-[4-(5-Amino-1,3,4-thiadiazol-2-yl)butyl]-3-pyridazinyl]-3-(trifluoromethoxy)benzeneacetamide;N-(6-(4-(5-amino-1,3,4-thiadiazol-2-yl)butyl)pyridazin-3-yl)-2-(3-(trifluoromethoxy)phenyl)acetamide(WXC05490);GlutaminaseIN3,Glutaminase IN 3;Benzeneacetamide, N-[6-[4-(5-amino-1,3,4-thiadiazol-2-yl)butyl]-3-pyridazinyl]-3-(trifluoromethoxy)- | | CAS: | 1439399-45-7 | | MF: | C19H19F3N6O2S | | MW: | 452.45 | | EINECS: | | | Product Categories: | | | Mol File: | 1439399-45-7.mol |  |
| | N-(6-(4-(5-Amino-1,3,4-Thiadiazol-2-Yl)Butyl)Pyridazin-3-Yl)-2-(3-(Trifluoromethoxy)Phenyl)Acetamide Chemical Properties |
| density | 1.437±0.06 g/cm3(Predicted) | | storage temp. | 4°C, protect from light | | solubility | DMSO : 50 mg/mL (110.51 mM; Need ultrasonic) | | form | Solid | | pka | 11.93±0.70(Predicted) | | color | Light yellow to yellow |
| | N-(6-(4-(5-Amino-1,3,4-Thiadiazol-2-Yl)Butyl)Pyridazin-3-Yl)-2-(3-(Trifluoromethoxy)Phenyl)Acetamide Usage And Synthesis |
| Biological Activity | Glutaminase-IN-3 (compound 657) is a potent glutaminase inhibitor with an IC50 of 0.24 μM for Glutaminase 1 (GLS1). Glutaminase-IN-3 is extracted from patent WO2014089048A1, compound 657[1]. | | References | [1]. Mark K. Bennett, et al. Treatment of cancer with heterocyclic inhibitors of glutaminase. WO2014089048A1. |
| | N-(6-(4-(5-Amino-1,3,4-Thiadiazol-2-Yl)Butyl)Pyridazin-3-Yl)-2-(3-(Trifluoromethoxy)Phenyl)Acetamide Preparation Products And Raw materials |
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