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ShangHai Caerulum Pharma Discovery Co., Ltd.
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18149758185 |
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sales-cpd@caerulumpharma.com |
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Product Name:N-(6-(4-(5-Amino-1,3,4-Thiadiazol-2-Yl)Butyl)Pyridazin-3-Yl)-2-(3-(Trifluoromethoxy)Phenyl)Acetamide CAS:1439399-45-7 Purity:98% Package:25g;5g;1g
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Shanghai CP Pharmaceutical Technology Co., Ltd.
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18221530285 |
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Product Name:N-(6-(4-(5-Amino-1,3,4-Thiadiazol-2-Yl)Butyl)Pyridazin-3-Yl)-2-(3-(Trifluoromethoxy)Phenyl)Acetamide CAS:1439399-45-7 Purity:95%+ Package:10g;25g;50g;100g,500g,1kg Remarks:L
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Wuxi AppTec
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022-59987777 13552403979 |
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jia_guoqiang@wuxiapptec.com |
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Product Name:N-(6-(4-(5-amino-1,3,4-thiadiazol-2-yl)butyl)pyridazin-3-yl)-2-(3-(trifluoromethoxy)phenyl)acetamide CAS:1439399-45-7 Purity:95%+ Package:1G,5G,10G,25G,50G,100G,250G Remarks:in stock
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Company Name: |
Aikon International Limited
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025-66113011 18112977050 |
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sales01@aikonchem.com |
Products Intro: |
Product Name:N-(6-(4-(5-Amino-1,3,4-Thiadiazol-2-Yl)Butyl)Pyridazin-3-Yl)-2-(3-(Trifluoromethoxy)Phenyl)Acetamide CAS:1439399-45-7 Purity:95+% Package:1g;5g;10g
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| N-(6-(4-(5-Amino-1,3,4-Thiadiazol-2-Yl)Butyl)Pyridazin-3-Yl)-2-(3-(Trifluoromethoxy)Phenyl)Acetamide Basic information |
Product Name: | N-(6-(4-(5-Amino-1,3,4-Thiadiazol-2-Yl)Butyl)Pyridazin-3-Yl)-2-(3-(Trifluoromethoxy)Phenyl)Acetamide | Synonyms: | N-(6-(4-(5-Amino-1,3,4-Thiadiazol-2-Yl)Butyl)Pyridazin-3-Yl)-2-(3-(Trifluoromethoxy)Phenyl)Acetamide;Glutaminase-IN-3;N-[6-[4-(5-Amino-1,3,4-thiadiazol-2-yl)butyl]-3-pyridazinyl]-3-(trifluoromethoxy)benzeneacetamide;N-(6-(4-(5-amino-1,3,4-thiadiazol-2-yl)butyl)pyridazin-3-yl)-2-(3-(trifluoromethoxy)phenyl)acetamide(WXC05490);GlutaminaseIN3,Glutaminase IN 3;Benzeneacetamide, N-[6-[4-(5-amino-1,3,4-thiadiazol-2-yl)butyl]-3-pyridazinyl]-3-(trifluoromethoxy)- | CAS: | 1439399-45-7 | MF: | C19H19F3N6O2S | MW: | 452.45 | EINECS: | | Product Categories: | | Mol File: | 1439399-45-7.mol | ![N-(6-(4-(5-Amino-1,3,4-Thiadiazol-2-Yl)Butyl)Pyridazin-3-Yl)-2-(3-(Trifluoromethoxy)Phenyl)Acetamide Structure](CAS/20180703/GIF/1439399-45-7.gif) |
| N-(6-(4-(5-Amino-1,3,4-Thiadiazol-2-Yl)Butyl)Pyridazin-3-Yl)-2-(3-(Trifluoromethoxy)Phenyl)Acetamide Chemical Properties |
density | 1.437±0.06 g/cm3(Predicted) | storage temp. | 4°C, protect from light | solubility | DMSO : 50 mg/mL (110.51 mM; Need ultrasonic) | form | Solid | pka | 11.93±0.70(Predicted) | color | Light yellow to yellow |
| N-(6-(4-(5-Amino-1,3,4-Thiadiazol-2-Yl)Butyl)Pyridazin-3-Yl)-2-(3-(Trifluoromethoxy)Phenyl)Acetamide Usage And Synthesis |
Biological Activity | Glutaminase-IN-3 (compound 657) is a potent glutaminase inhibitor with an IC50 of 0.24 μM for Glutaminase 1 (GLS1). Glutaminase-IN-3 is extracted from patent WO2014089048A1, compound 657[1]. | References | [1]. Mark K. Bennett, et al. Treatment of cancer with heterocyclic inhibitors of glutaminase. WO2014089048A1. |
| N-(6-(4-(5-Amino-1,3,4-Thiadiazol-2-Yl)Butyl)Pyridazin-3-Yl)-2-(3-(Trifluoromethoxy)Phenyl)Acetamide Preparation Products And Raw materials |
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